Results 31 to 40 of about 17,464 (169)

Evolving Practices in Prenatal Open Spinal Dysraphism: A Global Survey of Selection Criteria, Surgical Techniques, and Diagnostic Trends

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To provide an updated overview of international clinical practice in prenatal repair of open spinal dysraphism (OSD), focusing on evolving eligibility criteria, surgical techniques, and diagnostic standards. Methods A structured online survey was distributed to 83 fetal surgery centers worldwide.
Corinna Keil, Noemi Wiora, Eyal Krispin, Anita Windhorst, Roland Axt‐Fliedner, Ivonne Bedei   +5 more
wiley   +1 more source

Impaired Progesterone-Responsiveness of CD11c+ Dendritic Cells Affects the Generation of CD4+ Regulatory T Cells and Is Associated With Intrauterine Growth Restriction in Mice

Frontiers in Endocrinology, 2019
Up to 10% of pregnancies in Western societies are affected by intrauterine growth restriction (IUGR). IUGR reduces short-term neonatal survival and impairs long-term health of the children.
Kristin Thiele, Alexandra Maximiliane Hierweger, Julia Isabel Amambay Riquelme, María Emilia Solano, John P. Lydon, Petra Clara Arck   +5 more
doaj   +1 more source

Comparison of Metformin PBPK Models Incorporating Placental Transfer to Predict Fetal and Maternal Exposure

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Physiologically based pharmacokinetic (PBPK) modeling of placental drug transfer is an evolving tool for predicting fetal drug exposure. In this study, a pregnancy‐specific metformin PBPK model was developed, and the following four approaches were evaluated to predict metformin placental transfer: (1) perfusion‐limited model, and permeability ...
Jacqueline B. Tiley, Mattie E. Hartauer, Tajhia L. Whigham, Maïlys De Sousa Mendes, Kim L. R. Brouwer, Mary F. Hebert   +5 more
wiley   +1 more source

Timing of hospital admission for stillbirth delivery on maternal and obstetric outcome: a retrospective cohort study

Scientific Reports, 2021
The effect of timing of hospital admission for stillbirth delivery following late intrauterine fetal death (IUFD) has not yet been described. By this study, we aimed to gain an understanding of the impact of “immediate” (i.e., on the same day of IUFD ...
Dana Anaïs Muin, Anke Scharrer, Alex Farr, Herbert Kiss, Helmuth Haslacher   +4 more
doaj   +1 more source

Mono(2‐Ethylhexyl) Phthalate Induces Inflammatory and Angiogenic Alterations Mediated by the PI3K/AKT Pathway in HTR‐8/SVneo Trophoblastic Cells

Environmental Toxicology, EarlyView.
ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo, Ericka Karol Pamela Almeida‐Aguirre, Mariana Bobadilla‐Bravo, Ismael Mancilla‐Herrera, Alejandra Martínez‐Ibarra, Marco Cerbón   +5 more
wiley   +1 more source

Fetal Tele-Echocardiography—An Approach to Improving Diagnosis and Management

Diagnostics
Introduction: Antenatal diagnosis of cardiac abnormalities and counselling parents about postnatal care require a multidisciplinary team, which includes a paediatric cardiologist, a neonatologist, and a fetal medicine physician.
Badreldeen Ahmed, Amal Elsisi, Justin C. Konje   +2 more
doaj   +1 more source

Prognostic value of maternal N‐terminal pro‐B‐type natriuretic peptide for prediction of severe maternal adverse outcome in women with pre‐eclampsia

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), a marker of cardiac stress, has been proposed as a potential prognostic biomarker for maternal adverse outcome in pre‐eclampsia (PE). This study aimed to evaluate the predictive value of NT‐proBNP for severe maternal adverse outcome in pregnancies with an established diagnosis of
P. Palmrich, E. Kalafat, N. Schirwani‐Hartl, C. Haberl, T. Dorittke, L. Steinmetz, L. Krepler, J. Binder   +7 more
wiley   +1 more source

A dynamic analysis on foreign bank entry Nexus economic growth in Sub-Sahara African countries

Cogent Economics & Finance, 2021
This study investigated the direct link between foreign bank entry and economic growth in Sub-Sahara African countries using a dynamic generalized method of moment estimator. It also studied a comparative analysis on banking environment for SSA countries
Fetene Bogale Hunegnaw, Adem Feto Bedhaso   +1 more
doaj   +1 more source

In Suspected Fetal Growth Restriction, sFlt‐1/PlGF and PlGF May Have Value in Risk Stratification for Preterm Birth and Birthweight < 3rd Centile: A Blinded Cohort Study

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT We investigated the value of measuring sFlt‐1/PlGF in people with suspected fetal growth restriction (sFGR) without signs of preeclampsia at recruitment. Angiogenic biomarkers were considered positive when sFlt‐1/PlGF > 38 or PlGF < 100 pg/mL. Clinicians were blinded to the sFlt‐1/PlGF results.
Ruth C. E. Hughes, Pippa Kyle, Ian Phillips, Chris M. Florkowski, Joanna Gullam   +4 more
wiley   +1 more source

Advanced Paternal Age Impacts Common Loci in the Sperm and Placenta DNA Methylomes

Andrology, EarlyView.
ABSTRACT Background Epidemiological studies have reported an association between advanced paternal age at conception and an increased risk of neurodevelopmental disorders in offspring, such as autism spectrum disorder. Evidence suggests that DNA methylation alterations in spermatozoa of older men may be transmitted to the feto‐placental unit and ...
Julia Barnwell, Sophia Rahimi, Sherri Lee Jones, Donovan Chan, Josée Martel, Sara Abdessamie, Catherine M. Herba, Jean R. Séguin, William D. Fraser, Celia M. T. Greenwood, Tuong‐Vi Nguyen, Tina C. Montreuil, Jacquetta Trasler   +12 more
wiley   +1 more source