Results 91 to 100 of about 642,652 (383)

Defending the Distinction Between Pregnancy and Parenthood [PDF]

open access: yes, 2021
In this paper, I respond to criticisms toward my account of the difference in moral status between fetuses and newborns. I show my critics have not adequately argued for their view that pregnant women participate in a parent-child relationship.
Singh, Prabhpal
core  

Exposure to Prenatal Psychobiological Stress Exerts Programming Influences on the Mother and Her Fetus

open access: yesNeuroendocrinology, 2011
Background/Aims: Accumulating evidence from a relatively small number of prospective studies indicates that exposure to prenatal stress profoundly influences the developing human fetus with consequences that persist into childhood and very likely forever.
C. Sandman, E. Davis, C. Buss, L. Glynn
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Glomerulogenesis: Can it predict the gestational age? A study of 176 fetuses

open access: yesIndian Journal of Pathology and Microbiology, 2012
Background: Accurate assessment of gestational age of fetuses is essential from both clinical and medico-legal point of view. Crown-rump length, crown-heel length, foot length, and the weight of the fetus are the commonly used parameters for fetal age ...
Panduranga Chikkannaiah   +3 more
doaj   +1 more source

Direct evidence to support the role of HLA-G in protecting the fetus from maternal uterine natural killer cytolysis.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1997
HLA-G is a nonclassical major histocompatibility complex class I molecule selectively expressed on cytotrophoblasts at the feto-maternal interface, where it may play an important role in maternal tolerance of the fetus.
N. Rouas-Freiss   +4 more
semanticscholar   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Recent advances in sow nutrition Recentes avanços na nutrição de porcas

open access: yesRevista Brasileira de Zootecnia, 2010
Sows produce a larger number of fetuses than before and these fetuses possess genetic potentials to grow faster than before. Recent comparison shows that a porcine fetus is 40% heavier than 40 years ago.
Sung Woo Kim
doaj   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Innovative integration of automated breast volume scan and ultrasound elastography for enhanced differentiation of benign and malignant breast lesions

open access: yesScientific Reports
Breast cancer remains the most common malignancy among women and a leading cause of cancer-related mortality worldwide. Early detection through imaging is critical for improving patient prognosis.
Lamei Zhang   +5 more
doaj   +1 more source

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