Results 91 to 100 of about 447,204 (338)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Fetal intrapericardial teratomas

open access: yesThe Turkish Journal of Pediatrics, 2019
Fetal intrapericardial teratomas are rare and benign. However, they can be life-threatening owing to the complicated massive pericardial effusions, tamponade, or cardiorespiratory distress.
Shi-Min Yuan, Hong Lin
doaj   +1 more source

RETRACTED: Fetus-in-fetu in Botswana

open access: yesJournal of Pediatric Surgery Case Reports, 2017
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).This article has been retracted at the request of
Chowdhury Goutam, Francis Msume Banda
openaire   +3 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Ultrastructural and morphometrical peculiarities of embryo and fetus brainsynaptogenesis under conditions of prenatal ethanol exposure

open access: yesБюллетень сибирской медицины, 2008
The method of electron microscopy and morphometry have been used to study peculiarities in formation of the structure of human embryo and fetus brain synapses at early stages (7 to 12 weeks) of development at mother alcoholization. Electron microscopy of
A. V. Solonsky, S. V. Logvinov
doaj   +1 more source

The New Fetal Protection : The Wrong Answer to the Crisis of Inadequate Health Care for Women and Children [PDF]

open access: yes, 2006
This article will expand upon the feminist critique by focusing on children\u27s health as well as the health and liberty interests of their mothers. In the first part of this article, I examine the legal and cultural underpinnings of “fetal protection ...
Fentiman, Linda C.
core   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

State of the System «Placenta — Fetus — Newborn» in Pregnant Women with Disorders of Birth Canal Microbiota

open access: yesZdorovʹe Rebenka, 2015
Antenatal examination of the fetus and fetoplacental complex using computed tomography, ultrasonography and determination of fetal biophysical profile showed that chronic intrauterine fetal hypoxia with a reduction in adaptation possibilities of ...
Marvan Aussi, A.N. Matsynin
doaj   +1 more source

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