Results 51 to 60 of about 656,483 (352)

Why Doesn’t a Pregnant Woman Reject her Fetus [PDF]

open access: yes, 2011
Overview: Recurrent Pregnancy loss (RPL) occurs when a woman has three or more consecutive miscarriages; this phenomenon happens in about 1-3% of women. Why some women reject their unborn fetus and others carry theirs to term is still unclear.
Merry, Lisa
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Inside the Womb: Interpreting the Ferguson Case [PDF]

open access: yes, 2002
The rise of globalization has made ​​the sustainability aspect emerged as a sign that peoples’ actions must change. Tourism is now one of the fastest growing industries in the world that has an impact on people, nature and cultures.
Werauch, Samantha
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Born human as object of criminal law protection: Differentiation from the fetus [PDF]

open access: yesCrimen (Beograd)
Unlike most other goods, criminal law protection of human life is absolute. While e.g. property is protected by criminal law only in a subsidiary manner (if civil law mechanisms prove insufficient), only criminal law provides the appropriate sanction for
Vuković Igor
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Gut microbiota interacting with vitamin D but not anandamide might contribute to the pathogenesis of preeclampsia: a preliminary study

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionPreeclampsia (PE) is a pregnancy-specific multisystem disorder and a leading cause of maternal and perinatal mortality globally. Despite numerous studies highlighting the potential roles of gut microbiota, anandamide (AEA), and Vitamin D ...
Xiao-Qiang Han   +14 more
doaj   +1 more source

THE IMAGE OF EMBRYO AND FETAL OF ETAWA CROSSBRED GOATS USING ULTRASONOGRAPHY AT DIFFERENT GESTATIONAL AGES

open access: yesJurnal Kedokteran Hewan, 2018
This study aimed to estimate the gestational age of Etawa crossbred goats based on ultrasound images of embryo and fetal using transcutaneous ultrasonography.
Juli Melia   +6 more
doaj   +1 more source

Exposure to Prenatal Psychobiological Stress Exerts Programming Influences on the Mother and Her Fetus

open access: yesNeuroendocrinology, 2011
Background/Aims: Accumulating evidence from a relatively small number of prospective studies indicates that exposure to prenatal stress profoundly influences the developing human fetus with consequences that persist into childhood and very likely forever.
C. Sandman, E. Davis, C. Buss, L. Glynn
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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