Results 191 to 200 of about 1,463,292 (235)

Genetic etiologies with a large NGS panel in a monocentric cohort of 1000 patients with pediatric onset epilepsies

Epilepsia Open, EarlyView.
Abstract Objective Genetic testing is now included in the diagnostic assessment of childhood onset epilepsies. We evaluated the yield of a targeted next generation sequencing (TNGS) panel dedicated to pediatric epilepsies. Methods We tested by TNGS panel 1000 consecutive patients presenting with childhood onset epilepsies and including mainly patients ...
Giulia Barcia, Nicole Chemaly, Stéphanie Gobin‐Limballe, Emma Losito, Mélodie Aubart, Eugénie Sarda, Zahra Assouline, Pauline Plante‐Bordeneuve, Marie Hully, Remi Barrois, Christine Barnerias, Doxa Sareidaki, Delphine Coste Zeitoun, Monika Eisermann, Cécile Fourrage, Sylvain Hanein, Marlène Rio, Nathalie Boddaert, Isabelle Desguerre, Anna Kaminska, Julie Steffann, Rima Nabbout   +21 more
wiley   +1 more source

Visceral Leishmaniasis in Pediatrics: A Case Series and a Narrative Review with Global Insights. [PDF]

Trop Med Infect Dis
Andreottola V, Santucci C, Bellini T, Matarese S, Canzoneri F, Dell'Orso G, Finetti M, Fioredda F, Mesini A, Piccotti E.   +9 more
europepmc   +1 more source

Efficacy and tolerability of perampanel as add‐on therapy in Dravet syndrome: A prospective real‐world study

Epilepsia Open, EarlyView.
Abstract Objective To investigate the efficacy and tolerability of perampanel (PER) on Dravet syndrome in China by a prospective real‐world study. Methods We prospectively enrolled children with Dravet syndrome from the neurology clinic of Shenzhen Children's Hospital from September 2020 to October 2021.
Han Wang, Hong Chen, Xin Ding, Xueyan Cao, Jiahui Mai, Huafang Zou, Dongfang Zou, Yanwei Zhu, Jianxiang Liao, Dezhi Cao   +9 more
wiley   +1 more source

Typhoid Fever Presenting With Cerebral Venous Thrombosis: A Report of a Rare Case. [PDF]

Cureus
Oulalite A, Mimouni H, Jartit M, Bkiyar H, Housni B.   +4 more
europepmc   +1 more source

Exploring the Potential and Advancements of Circular RNA Therapeutics

Exploration, EarlyView.
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang, Lianqing Wang, Chunbo Dong, Jialong Liu, Guoxin Cui, Shan Gao, Zhida Liu   +6 more
wiley   +1 more source

Predictors of Persistent Fever Among Patients With Suspected Infective Endocarditis: Think Outside the box. [PDF]

Clin Infect Dis
Stavropoulou E, Monney P, Tzimas G, Ianculescu N, Tozzi P, Kirsch M, Guery B, Papadimitriou-Olivgeris M.   +7 more
europepmc   +1 more source

Synthetic Biology‐Based Engineering Living Therapeutics for Antimicrobial Application

Exploration, EarlyView.
This perspective highlights synthetic biology‐driven antibacterial strategies, focusing on three innovative approaches: engineered bacteriophages for precision bacterial targeting, reprogrammed microbes that detect quorum‐sensing signals or metabolites to release antimicrobials, and engineering mammalian cells that recognize pathogen‐associated ...
Shun Huang, Shuihao Zhao, Haijie Zhao, Mingzhang Wen, Zhong Guo   +4 more
wiley   +1 more source

Pancreatitis as a Rare Complication of Dengue Fever: A Case Report and Review of the Literature. [PDF]

Cureus
Alnuaimi MK, Alsubai JA, Alnuaimi A.
europepmc   +1 more source

Application of Bryophytes to Foods, Food Additives and Phytomedicines

Food Chemistry International, EarlyView.
Little attention has been paid to the bryophytes for use in the human diet, despite the presence of 23,000 species worldwide. (Marchantia polymorpha). ABSTRACT Little attention has been paid to the bryophytes for application on the human diet, despite the presence of 23,000 species worldwide.
Yoshinori Asakawa, Jianbo Xiao
wiley   +1 more source

Development and validation of a nomogram for predicting necrotizing pneumonia in children with refractory Mycoplasma pneumoniae pneumonia. [PDF]

Ital J Pediatr
Li X, Zhao L, Cui X, Xu Y, Zhang T, Guo W, Ning J.   +6 more
europepmc   +1 more source