Results 41 to 50 of about 75,941 (261)

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Fever of unknown origin in rheumatology

Современная ревматология, 2018
The article considers the current state of the problem related to fever of unknown origin (FUO). It highlights the main stages of studying this issue with a detailed description of the classification diagnostic criteria, etiological types, and clinical ...
A. V. Gordeev, N. M. Savushkina, E. A. Galushko   +2 more
doaj   +1 more source

Fever of unknown origin

Saudi Medical Journal, 2003
This report describes a 3-year-old female child with prolonged fever in which a very extensive work-up resulted in the discovery of the underlying congenital anomaly causing her symptom.
openaire   +2 more sources

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

DELAY IN DIAGNOSIS OF MALARIA BECAUSE OF IMPROPER EFFECTS OF ANTIBIOTIC THERAPY

Iranian Journal of Public Health, 2000
Although most parts of Iran is free of malaria owing to appreciable struggle against this disease by the Ministry of Public Health, in every case of fever of unknown origin (FUO) possibility of malaria should not be neglected.
M. Jalali Tabatabai, P. Vosough, H. Samadpour, Sh. Yousefi   +3 more
doaj  

FEVER OF UNKNOWN ORIGIN: DESCRIPTIVE STUDY

Архивъ внутренней медицины, 2019
Background: fever of unknown origin is one of the diagnoses more difficult in our area, because it involves monitoring of a complex algorithm of several procedures to establish its cause and con frequently takes too long before any explanation. Therefore,
Yu. A. Perova, N. Ramos Vicente, L. Alandete German, J. Izquierdo Alabau, G. Fernando Lascurain, J. Martinez Mendieta, D. M. Sanchez Escobedo   +6 more
doaj   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source

Pheochromocytoma presenting as fever of unknown origin, a case report

Case Reports, 2020
Introduction: Pheochromocytoma is a generally benign neoplasm derived from chromaffin cells of the adrenal medulla. It is characterized by the production of large amounts of catecholamines and also by the capacity to secrete bioactive peptides such as ...
Angélica María González-Clavijo, Juan David Muñoz-Loaiza, Jennifer Daniela Guzmán-Rojas, Johiner Jahir Vanegas-Antolinez, Laura Natalia Bermúdez-Silva, Luis Felipe Fierro-Maya   +5 more
doaj   +1 more source

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source