Results 51 to 60 of about 75,941 (261)

A Report of Subacute Thyroiditis As Fever of Unknown Origin

پزشکی بالینی ابن سینا, 2002
Patients  with  subacute  or granulomatous  thyroiditis  usually come to    the physician with fever , Anterior cervical pain and they show  tenderness    in palpation during phyical  examination .
Mitra Ranjbar, Mohammad Mohammadtaheri, Reza Zaeemkohan   +2 more
doaj  

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

A case of fever of unknown origin – Was it really unknown?

APIK Journal of Internal Medicine, 2022
A 66-year-old male patient with diabetes and hypertension presented with a history of 2 months of continuous fever and weight loss. He was investigated earlier and treated for upper respiratory infection, typhus, and other infections with no reduction in
Manjunath Premanath
doaj   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

Peripherally inserted central catheter line-induced fevers: a case report

Journal of Medical Case Reports
Background Peripherally inserted central catheter lines are increasingly common as medical innervation advances. Peripherally inserted central catheter lines are generally well tolerated with few complications, the most common being pain, bleeding, line ...
Catherine van’t Hoff, Benjamin H. L. Harris, Ahilan Kailaya-Vasan, Michael B. Fertleman, Louis J. Koizia   +4 more
doaj   +1 more source

A Common But Usually Overlooked Cause of Fever of Unknown Origin: Still’s Disease

Bagcilar Medical Bulletin, 2022
A wide variety of causes, ranging from bacterial or viral infections to malignancies, may be responsible from the development of fever of unknown origin (FUO).
Caner Varhan, İhsan Solmaz, Süleyman Özçaylak, Zeynep Kutlu, Elif Anık, Ahmet Engin Atay   +5 more
doaj   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

A PROSPECTIVE STUDY OF BRUCELLOSIS IN CHILDREN: RELATIVE FREQUENCY OF PANCYTOPENIA

Mediterranean Journal of Hematology and Infectious Diseases, 2013
Hematological complications in brucellosis are common. Pancytopenia, although mainly reported in adults has also been described in children with brucellosis.
Mohamed El Koumi, Mona Afify, Salha Al-Zahrani   +2 more
doaj   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source