Results 211 to 220 of about 35,241 (222)

FGFR2 inhibition could suppress spermatogenesis.

Journal of Clinical Oncology, 2020
e15659 Background: The incidence of cancer among the people of reproductive age is constantly increasing. Although FGF2/FGFR2 expression in the male reproductive tract has been reported, there is no evidence of the impact of FGFRs inhibitors on sperm function.
Ilya Tsimafeyeu, Nataliya Lapina, Mikhail Byakhov, Nadezhda Dragun, Evgenia Gavrilova, Anastasia Skorobogatova, Kira Stosman, Marina Melikhova, Olga Vakunenkova, Vadim Kashuro, Mikhail Rozhko, Sergei Tjulandin   +11 more
openaire   +1 more source

Clustering of FGFR2 gene mutations inpatients with Pfeiffer and Crouzon syndromes (FGFR2-associated craniosynostoses)

Cytogenetic and Genome Research, 2000
A cohort of 36 unrelated German patients with craniosynostosis syndromes of the Crouzon and Pfeiffer type were analyzed for FGFR mutations. Mutations in FGFR2 were identified in 25 Crouzon and 5 Pfeiffer syndrome patients, whereas no sequence alterations were found in the remaining patients, even after screening of the relevant parts of FGFR1, FGFR3 ...
W, Kress, H, Collmann, M, Büsse, B, Halliger-Keller, C R, Mueller   +4 more
openaire   +2 more sources

Modulation of the expression of the FGFR2-IIIb and FGFR2-IIIc molecules in dermatofibroma

Journal of Dermatological Science, 2008
[No abstract available]
SKROZA, Nevena, Sabrina Rotolo, CECCARELLI, SIMONA, ROMANO, Ferdinando, Daniele Innocenzi, FRATI, Luigi, ANGELONI, Antonio, MARCHESE, Cinzia   +7 more
openaire   +3 more sources

Mutation detection in FGFR2 craniosynostosis syndromes

Human Genetics, 1997
Five autosomal dominant craniosynostosis syndromes (Apert, Crouzon, Pfeiffer, Jackson-Weiss and Crouzon syndrome with acanthosis nigricans) result from mutations in FGFR genes. Fourteen unrelated patients with FGFR2-related craniosynostosis syndromes were screened for mutations in exons IIIa and IIIc of FGFR2.
Hollway, G., Suthers, G., Haan, E., Thompson, E., David, D., Gecz, J., Mulley, J.   +6 more
openaire   +3 more sources

FGFR2: A pan-genomic target.

Journal of Clinical Oncology, 2019
3099 Background: FGFR2 genomic alterations (GA) have been described in a variety of solid tumors and emerged as biomarkers for investigational agents undergoing clinical trials. Methods: 201,766 primarily relapsed/refractory malignancies were evaluated with a hybrid-capture based sequencing assay Tumor mutational burden (TMB) was determined on 0.8-1 ...
Russell Madison, Ethan Sokol, Alexa Betzig Schrock, Adrienne Johnson, Dean Pavlick, Julia Andrea Elvin, Jo-Anne Vergilio, Nhu Ngo, Jonathan Keith Killian, Douglas I. Lin, Shakti Ramkissoon, Eric Allan Severson, Amanda Hemmerich, Daniel Duncan, Siraj Mahamed Ali, Prasanth Reddy, Kimberly McGregor, Brian Alexander, Vincent A. Miller, Jeffrey S. Ross   +19 more
openaire   +1 more source

Wnt-TCF7-SOX9 axis promotes cholangiocarcinoma proliferation and pemigatinib resistance in a FGF7-FGFR2 autocrine pathway

Oncogene, 2022
Zeng-li Liu, Jialiang Liu, Tianli Chen, Yue Wang, A. Shi, Kangshuai Li, Xing-Guo Li, B. Qiu, Li-jie Zheng, Li-ming Zhao, Lizhuang Shu, Shuo Lian, Shao-hui Huang, Zongli Zhang, Yunfei Xu   +14 more
semanticscholar   +1 more source

FGFR2

1995
M. Jaye, I. Lax, M. Mohammadi, J. Schlessinger   +3 more
openaire   +1 more source

FGFR2 mutations and acne

The Lancet, 1998
openaire   +2 more sources

FGFR2/3 related Syndromes

2009
Robert J. Desnick, Orlando Guntinas-Lichius, George W. Padberg, Gustav Schonfeld, Xiaobo Lin, Maurizio Averna, Pin Yue, John-John B. Schnog, Victor E. A. Gerdes, Pedro R. Cutillas, Robert J. Unwin, Heike Schulze, Konrad Sandhoff, Jean-François Pellissier, Georges Serratrice, Dominique Figarella-Branger, Cord Sunderkötter, Marcelo Gustavo Binker, Laura Iris Cosen-Binker, Matthias Wettstein, Peter von den Driesch, Rima Nabbout, Massimo Mantegazza, Olivier Dulac, Johann Michael Schröder, Ho Sung Kang, Johann Michael Schröder, Marina Marchetti Hugo Ten Cate, Marina Marchetti, Hugo ten Cate, Lev I. Patrushev, Lee S. Weinstein, Adiba Isa, Fernando Azpiroz, Guang-Sheng Li, Ling Jing, Hui Xu, Anne M. Molloy, John M. Scott, Cord Sunderkötter, Axel Lorentz, Stephan C. Bischoff, Filippo Tamanini, Filippo Tamanini, Thomas Klockgether, Derek A. Wong, Jürgen Kopitz, Carolina von Reitzenstein, Michael Cantz   +48 more
openaire   +1 more source

FGFR2/3 im Urothelkarzinom

Die Pathologie
Michael Rose, Nadine T. Gaisa
openaire   +1 more source