Results 41 to 50 of about 818,714 (249)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Multi-element fiber for space-division multiplexing

, 2013
A novel approach of using multi-element fiber (MEF) technology in space-division multiplexing (SDM) systems is presented. This paper reviews the progress in fabrication and characterization of MEF based both ultra-low crosstalk transmission and amplifier
V. J. F. Rancaño, May-Smith, T.C., Petropoulos, P., Jain, S., Richardson, D.J., T. C. May-Smith, S. Jain, J. K. Sahu, D. J. Richardson, P. Petropoulos, Sahu, J.K., Rancaño, V.J.F., A. Webb, Webb, A.   +13 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Widely Tunable Pulse Duration 100 mJ Single-Mode MOPA System Based on Yb-Doped Tapered Double-Clad Fiber and Nd:YAG Solid-State Amplifiers

Photonics
We report on a 1064 nm master oscillator power amplifier (MOPA) system based on pulse-modulated laser diode seed sources combined with fiber preamplifiers and a Yb-doped tapered double-clad fiber (T-DCF) amplifier used as an all-fiber master oscillator ...
Mikhail Kozlyakov, Andrey Petrov, Grigoriy Mikhailovskiy   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Characterization of the semiconductor optical amplifier for amplification and photonic switching employing the segmentation model [PDF]

, 2008
This paper characterizes the gain and the carrier density responses of a semiconductor optical amplifier (SOA). In order to achieve the switching functions in SOA-based optical switches, such as Symmetric Mach-Zehnder (SMZ), the effect of the input ...
Ghassemlooy, Zabih, Ng, Wai Pang, R. Ngah, Z. Ghassemlooy, Moustafa H. Aly, Aly, Moustafa, M. F. Chiang, Chiang, Ming-Feng, Ngah, Razali, Abd El Aziz, W. P. Ng, Abd El Aziz, Ahmad   +11 more
core   +1 more source

Think Outside the Fiber: Imaging Amplifier for Space-Multiplexed Optical Transmission

IEEE Photonics Journal, 2012
This paper proposes a simple and practical method to amplify signals for space-multiplexed optical transmission. In this amplification technique, the output facet of the multicore or multimode fiber is mapped back to the same type of fiber after passing ...
Ibrahim Ozdur, Hong Shu, Michael Bass, Guifang Li   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Coupled experiment/simulation approach for the design of radiation-hardened rare-earth doped optical fibers and amplifiers [PDF]

, 2011
We developed an approach to design radiation-hardened rare earth -doped fibers and amplifiers. This methodology combines testing experiments on these devices with particle swarm optimization (PSO) calculations.
F. Prudenzano, Mescia, L, Vivona, M., Girard, S, Boukenter, Aziz, A. Boukenter, Goiffon, V, Cannas, M., V. Goiffon, Mescia, Luciano, Boukenter, A, L. Mescia, Vivona, Marilena, Mescia, L., R. Boscaino, Cadier, B., P. Paillet, Paillet, P., Y. Ouerdane, Boukenter, A., Paillet, P, Paillet, Philippe, Marcandella, C, Cadier, Benoît, S. Girard, A. Laurent, Laurent, A, Robin, T, C. Marcandella, Goiffon, Vincent, Cadier, B, Ouerdane, Y., Ouerdane, Y, Girard, Sylvain, Prudenzano F, Robin, Thierry, F. Robin, Prudenzano, F, Laurent, Arnaud, Boscaino, Roberto, T. Robin, Robin, T., B. Cadier, Marcandella, C., Goiffon, V., Cannas, Marco, M. Cannas, Prudenzano, F., Boscaino, R., Prudenzano, Francesco, Ouerdane, Youcef, M. Vivona, Girard, Sébastien, Marcandella, Claude, Laurent, A.   +54 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source