Results 91 to 100 of about 6,776,291 (296)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Characteristics of Q-switched cladding-pumped ytterbium-doped fiber lasers with different high-energy fiber designs

, 2001
We theoretically and experimentally analyze Q-switched cladding pumped ytterbium-doped fiber lasers designed for high pulse energies. We compare the extractable energy from two high-energy fiber designs: (1) single- or few-moded low-NA large mode area ...
Alvarez-Chavez, J.A., Clarkson, W.A., Nilsson, J., Offerhaus, H.L., Turner, P.W., Renaud, Cyril C., Richardson, D.J., Grudinin, A.B.   +7 more
core   +1 more source

Self-Referencing Fiber-Optic Intensity Sensors Using Ring Resonators and Fiber Bragg Gratings [PDF]

, 2006
An improved ring resonator self-referencing technique in a new reflection configuration for remote fiber-optic intensity sensors is demonstrated using fiber Bragg gratings. Sensor sensitivity doubles and a single fiber lead is used.
Sánchez-Pena, José Manuel, Vázquez García, María Carmen, Montalvo García, Julio, Sánchez Montero, David Ricardo   +3 more
core   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Substantiation of optimal parameters of rapeseed cake extrusion process [PDF]

Caspian Journal of Environmental Sciences
The inclusion of rapeseed products in animal and poultry feeds is hindered by the presence of low-nutrient compounds like erucic acid, glucosinolates, tannins, and phytic acid, which can be harmful and reduce overall productivity. This study investigates
Torebek Bаib`atyrov, Saule Zhienbayeva, Altynai Abuova, Askhat Umbetbekov, Mahamedkali Kenzhekhodzhaev, Zhamilya Mazhit, Zhazira Mukazhanova, Shynar Sanyazova   +7 more
doaj   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Dynamic Parameters of Fiber-Reinforced Soils at Very Small Strains

Fibers
Improvement of the engineering properties of soils by reinforcing them with fibers, at an appropriate percentage of the weight of dry soil, is frequently selected to ensure the safe construction and operation of many structures.
Konstantinos E. Bantralexis, Eleni S. Boura, Ioannis N. Markou, Evangelos D. Evangelou   +3 more
doaj   +1 more source