Results 71 to 80 of about 854,089 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Speciation without chromatography: Part I. Determination of tributyltin in aqueous samples by chloride generation, headspace solid-phase microextraction and inductively coupled plasma time of flight mass spectrometry [PDF]

, 2001
An analytical procedure was developed for the determination of tributyltin in aqueous samples. The relatively high volatility of the organometal halide species confers suitability for their headspace sampling from the vapour phase above natural waters or
Lam, J., Maxwell, P., Mester, Z., Peter, L., Sturgeon, R.   +4 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Effect of Fiber Content on Mechanical Properties and Microstructural Characteristics of Alkali Resistant Glass Fiber Reinforced Concrete

Advances in Materials Science and Engineering, 2022
Owing to its enhanced strength, ductility, and resistance to harsh environments, increasing research attention has been paid to alkali-resistant glass fiber reinforced concrete (ARGFRC).
Chao Wu, Xiongjun He, Xia Zhao, Li He, Yuan Song, Xiuyan Zhang   +5 more
doaj   +1 more source

Promising hybrid lines of fiber flax with high content of fiber

Siberian Herald of Agricultural Science, 2020
The paper presents the results of creating a material for obtaining an early ripening variety of fiber flax for cultivation in Siberia, characterized by high-quality fiber and a high degree of adaptability to external environmental factors, resistance to lodging and diseases.
G. A. Popova, O. I. Polyakova, N. V. Knyazeva, N. B. Rogalskaya, V. M. Trofimova   +4 more
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Fiber Content, Reduced Sugar and Organoleptic Quality of Nata De Avocado on The Variation Types of Sugar and Nutrition

Quagga
Nata is a probiotic food fermented with the starter Acetobacter xylinum bacteria. Avocado has the potential as nata substrate containing carbohydrates, protein, iron, vitamin A, vitamin B and fat.
Desty Sekar Prameswari, Titik Suryani
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Black Beans, Fiber, and Antioxidant Capacity Pilot Study: Examination of Whole Foods vs. Functional Components on Postprandial Metabolic, Oxidative Stress, and Inflammation in Adults with Metabolic Syndrome. [PDF]

, 2015
Beans (Phaseolus vulgaris) contain bioactive components with functional properties that may modify cardiovascular risk. The aims of this pilot study were to evaluate the ability of black beans to attenuate postprandial metabolic, oxidative stress, and ...
Burton-Freeman, Britt M, Edirisinghe, Indika, Kappagoda, C Tissa, Randolph, Jody M, Reverri, Elizabeth J, Steinberg, Francene M   +5 more
core   +3 more sources

Improving the Dietary Fiber Content of Tapioca Using Corn Fiber as a Fiber Supplement

International Journal of Innovative Science and Research Technology (IJISRT)
This research aims to enhance the dietary fiber content of locally produced cassava (manihot spp) food, tapioca, by incorporating corn (Zea mays) as a fiber supplement. Tapioca was prepared by grating cassava into coarse particles and washing it with water to remove starch.
Ukwesan, Godwin Tejiri, Iyasele, Julius, Ediale, Abraham Omo, MOMODU- MOMOH, Shemahu, AJAYI, Bernard Ojeizuanbi, OGIEMUDIA, Odion Paul   +5 more
openaire   +1 more source