Results 51 to 60 of about 1,638,876 (299)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Characteristics of Collimators Based on the Large-Mode-Area CMCF for Coupling Laser Beam

open access: yesApplied Sciences, 2021
A new collimator based on a homemade concentric multilayer-core fiber (CMCF) is proposed and experimentally demonstrated. This collimator was fabricated using a tail fiber with large mode area and single-mode operation.
Xuran Zhang   +5 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Distributed Polarization and Coupling Analysis of a 3-Coupled-Core Fiber [PDF]

open access: yes, 2023
OFDR-based, distributed characterization of polarization and coupling properties of a 3-coupled-core fiber is reported. Results highlight the beating among the supermodes of the fiber, enabling the evaluation of their polarization and modal ...
Chen, Haoshuo   +9 more
core   +1 more source

Study on the Influence of Atmospheric Light Intensity Scintillation Effect on Optical Fiber Coupling Efficiency

open access: yesPhotonics
Light intensity flicker is the most basic and important effect of turbulence. Fiber coupling efficiency is the primary parameter that ensures the system’s communication quality.
Xiaoying Ding, Xin Zhao
doaj   +1 more source

Investigation on the Coupling of Vortex Beam Into Parabolic Fiber in Turbulent Atmosphere

open access: yesIEEE Photonics Journal, 2019
Aiming at the demand for high-capacity wireless-fiber link, the coupling efficiency of Laguerre Gaussian (LG) vortex beam into parabolic fiber under atmospheric turbulence is first investigated.
Lin Yu, Yixin Zhang
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Single-mode fiber length for wavefront filtering

open access: yes, 2008
Stellar nulling interferometry offers the possibility of direct imaging of extrasolar planets necessary for the detection of extra-terrestrial life. Achieving optimum performance from the interferometers requires that the wavefronts of light reaching the
Dasgupta, Sonali   +2 more
core   +1 more source

Research on an Adaptive Coupling Technique for Spatially Scattered Light

open access: yesSensors
Focusing on the problems of difficult alignment and low efficiency when coupling the spatially scattered light from 532 nm underwater LiDAR to a single-mode fiber, this paper presents an analysis and simulation of the coupling principle of spatially ...
Xin Liu   +6 more
doaj   +1 more source

A Numerical–Experimental Approach for Multi‐Matrix Fiber‐Reinforced Plastics Characterization Using Finite Element Model Updating

open access: yesAdvanced Engineering Materials, EarlyView.
A numerical–experimental framework is developed for characterizing multi‐matrix fiber‐reinforced polymers (MM‐FRPs) combining epoxy and polyurethane matrices. Harmonic bending tests are integrated with finite element model updating (FEMU) to simultaneously identify elastic and viscoelastic material parameters.
Rodrigo M. Dartora   +4 more
wiley   +1 more source

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