Results 51 to 60 of about 1,912,482 (249)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Recent Advancements of LSPR Fiber-Optic Biosensing: Combination Methods, Structure, and Prospects

Biosensors, 2023
Fiber-optic biosensors based on localized surface plasmon resonance (LSPR) have the advantages of great biocompatibility, label-free, strong stability, and real-time monitoring of various analytes.
Hongxin Zhang, Xue Zhou, Xuegang Li, Pengqi Gong, Yanan Zhang, Yong Zhao   +5 more
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

The detection of ultrasound using fiber-optic sensors [PDF]

, 2007
Ultrasound is a valuable tool for the detection of damage in structures and the characterization of material properties. Its detection is conventionally done by piezoelectric transducers, however fiber-optic sensors can operate over a greater range of ...
Culshaw, B., Thursby, G., Betz, Daniel, Thursby, G.J., Betz, D., Brian Culshaw, Sorazu, B.L., Graham Thursby, Daniel Betz, Boja Sorazu, Sorazu, B., Thursby, Graham, Sorazu, Borja, Culshaw, Brian   +13 more
core   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Quantitative sensitivity analysis of surface attached optical fiber strain sensor [PDF]

, 2014
Optical fiber strain sensors, in particular, the fiber Bragg grating (FBG) type, are widely applied in different applications. The most common installation method is surface-attached.
Wan, KT
core   +1 more source

Two-Channel SPR Sensor Combined Application of Polymer- and Vitreous-Clad Optic Fibers

Sensors, 2017
By combining a polymer-clad optic fiber and a vitreous-clad optic fiber, we proposed and fabricated a novel optic fiber surface plasmon resonance (SPR) sensor to conduct two-channel sensing at the same detection area.
Yong Wei, Yudong Su, Chunlan Liu, Xiangfei Nie, Zhihai Liu, Yu Zhang, Yonghui Zhang   +6 more
doaj   +1 more source

Subclinical Optic Nerve Involvement in Radiologically Isolated Syndrome: Multimodal Detection and Diagnostic Impact

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We aimed to determine the frequency of subclinical optic nerve (ON) lesions using MRI, optical coherence tomography (OCT), and visual evoked potentials (VEP) in radiologically isolated syndrome (RIS), and to assess their diagnostic and prognostic significance.
Christine Lebrun‐Frenay, Cassandre Landes‐Château, Lydiane Mondot, Mikael Cohen, Margherita Popolo, Jérôme de Seze, Bertrand Bourre, Françoise Durand‐Dubief, Olivier Casez, Orhun H. Kantarci, Aksel Siva, Stephanie Baillif, Darin T. Okuda, Letizia Leocani   +13 more
wiley   +1 more source

Multi-sensor system using plastic optical fibers for intrinsically safe level measurements [PDF]

, 2004
A system for measuring liquid level in multiple tanks using optical fibe technology has been developed. Oil fiel service industry or any sector requiring liquid level measurements in flammabl atmospheres can be benefite from this intrinsically safe ...
Gonzalo, Ana B., Vázquez García, María Carmen, Montalvo García, Julio, Vargas Palma, Salvador Elías, Vázquez, Carmen, Vargas, Salvador E., Montalvo, Julio   +6 more
core   +1 more source