Results 61 to 70 of about 200,851 (352)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Edible oils adulteration analysis by fiber optic multimode displacement sensor [PDF]

, 2022
A fiber optic sensor has been developed to detect the adulteration in edible oil, particularly coconut oil. In this paper, the sensing mechanism uses MMF-MMF based on displacement sensors by employing the lateral offset method.
Othman, Maisara, Nordin, Siti Noraminah, Haroon, Hazura, Anbalagan, Thanigai   +3 more
core  

In situ detection of spatial distribution information of temperature-pH-strain of sandstone cultural relics

npj Materials Degradation
To monitor in situ the temperature, pH, and micro-strain change information of sandstone artifacts in the process of oxalic acid corrosion, the temperature, pH, and micro-strain fiber Bragg grating (FBG) sensors are developed.
Changyuan Xu, Linyang Li, Rong Hu, Huihua Wu, Lingnan Kong, Nianbing Zhong, Bo Wan, Lei Wu, Dong Lai, Yuanyuan He, Yang Liu, Xiaoling Peng, Mingfu Zhao, Quanhua Xie   +13 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient fiber Bragg grating and fiber Fabry-Pe'rot sensor multiplexing scheme using a broadband pulsed mode-locked laser

, 2005
A pulsed broadband mode-locked laser (MLL) combined with interferometric interrogation is shown to yield an efficient means of multiplexing a large number of fiber Bragg grating (FBG) or fiber Fabry-Perot (FFP) strain sensors with high performance ...
Flockhart, G M H, Cranch, G A, Kirkendall, C K   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

All-fiber-optic vector magnetic field sensor based on side-polished fiber and magnetic fluid.

Optics Express, 2019
A kind of compact all-fiber-optic vector magnetic sensor is proposed and demonstrated. The sensor consists of a side-polished-fiber (SPF)-integrated with singlemode-no core-singlemode (SNS) fiber structure.
Yongxi Li, Shengli Pu, Yongliang Zhao, Rui Zhang, Zixuan Jia, Jilei Yao, Zijian Hao, Zhongxue Han, Dihui Li, Xinjie Li   +9 more
semanticscholar   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Efficient large-scale multiplexing of fiber Bragg grating and fiber Fabry-Perot sensors for structural health monitoring applications

, 2006
Fiber Bragg gratings have been demonstrated as a versatile sensor for structural health monitoring. We present an efficient and cost effective multiplexing method for fiber Bragg grating and fiber Fabry-Perot sensors based on a broadband mode-locked ...
Kirkendall, C. K., Flockhart, G. M. H., Cranch, Geoffrey A.   +2 more
core   +1 more source

Development of Miniaturized Fiber-Optic Laser Doppler Velocimetry Sensor for Measurement of Local Blood Velocity

Journal of Fluid Science and Technology, 2009
A new miniaturized fiber-optic laser Doppler velocimetry (LDV) sensor has been developed, which is capable of measuring the local velocity in various semi-opaque and opaque fluid flows, particularly whole blood velocity in vessels.
Tsutomu TAJIKAWA, Mitsuhiko TAKESHIGE, Wataru ISHIHARA, Shimpei KOHRI, Kenkichi OHBA   +4 more
doaj   +1 more source