Results 51 to 60 of about 329,923 (395)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Intraluminal measurement of papillary duct urine pH, in vivo: a pilot study in the swine kidney [PDF]

, 2015
We describe the in vivo use of an optic-chemo microsensor to measure intraluminal papillary duct urine pH in a large mammal. Fiber-optic pH microsensors have a tip diameter of 140-µm that allows insertion into papillary Bellini ducts to measure tubule ...
Bledsoe, Sharon B., Connors, Bret A., Evan, Andrew P., Handa, Rajash K., Johnson, Cynthia D., Lingeman, James E.   +5 more
core   +1 more source

Electric Field-Enhanced SPR Sensors with AuNPs and CQDs for Rapid and Low-Detection-Limit Detection of Co²⁺

Solids
As a vital transition metal species, cobalt ions (Co2+) play a critical role in industrial and medical fields. However, uncontrolled release into ecosystems via industrial effluents presents significant environmental risks.
Xinyue Jing, Minxuan Chen, Xingye Ma, Xinrui Xu, Ning Wang, Kunpeng Niu, Xiaohan Chen, Yihao Wang, Jiayi Zhu, Jianguo Hou, Zhichao Wang   +10 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Galloping Vibration Monitoring of Overhead Transmission Lines by Chirped FBG Array

Photonic Sensors, 2022
A distributed online fiber sensing system based on the phase-sensitive optical time domain reflectometer (Φ-OTDR) enhanced by the drawing tower fiber Bragg grating (FBG) array is presented and investigated experimentally for monitoring the galloping of ...
Qizhong Yan, Ciming Zhou, Xuebin Feng, Chi Deng, Wenyu Hu, Yimin Xu   +5 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Long Short-Term Memory Neural Network with Transfer Learning and Ensemble Learning for Remaining Useful Life Prediction

Sensors, 2022
Prediction of remaining useful life (RUL) is greatly significant for improving the safety and reliability of manufacturing equipment. However, in real industry, it is difficult for RUL prediction models trained on a small sample of faults to obtain ...
Lixiong Wang, Hanjie Liu, Zhen Pan, Dian Fan, Ciming Zhou, Zhigang Wang   +5 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Self-Referencing Fiber-Optic Intensity Sensors Using Ring Resonators and Fiber Bragg Gratings [PDF]

, 2006
An improved ring resonator self-referencing technique in a new reflection configuration for remote fiber-optic intensity sensors is demonstrated using fiber Bragg gratings. Sensor sensitivity doubles and a single fiber lead is used.
Montalvo García, Julio, Sánchez Montero, David Ricardo, Sánchez-Pena, José Manuel, Vázquez García, María Carmen   +3 more
core   +2 more sources