Results 41 to 50 of about 334,806 (219)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Selena - a new cotton variety

open access: yesРастениевъдни науки
The aim of this research was to study the productive potential and evaluate the fiber properties of the new Selena cotton variety. The variety was studied in competition variety trials conducted in 2017-2022 in the experimental field of the Field Crops ...
Valentina Dimitrova   +1 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Evaluation of the OpTest Fiber Quality Analyzer for Quantifying Cotton and Rayon Microfibers

open access: yesFibers
Microfibers are small fiber particles that separate from larger textiles through wear abrasion or home laundering. Pervasive accumulation of synthetic microfibers in the environment is motivating efforts to quantify them, and to gain a better ...
Michael Santiago Cintron   +1 more
doaj   +1 more source

Borosilicate Based Hollow-Core Optical Fibers

open access: yesFibers, 2019
We discuss the fabrication of hollow-core optical fibers made of borosilicate glass. We show that, despite the high attenuation of the glass relative to silica, the fiber optical losses can be of the same order of magnitude of those obtained by using ...
Walter Belardi, Pier John Sazio
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Türkiye’de Doğal Olarak Yetişen Titrek Kavak Odununun (populus tremula L.) Lif Morfolojisi ve Kimyasal Yapısının İncelenmesi

open access: yesDüzce University Faculty of Forestry Journal of Forestry, 2013
Bu çalışmada titrek kavak (Populus tremula L.) ağacının kimyasal analizleri ve lif yapısı incelenmiştir. Titrek kavak odunu, Bartın orman işletme müdürlüğüne bağlı Arıt şefliğinden temin edilmiştir.
Mehmet Onurhan Gücüş   +1 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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