Results 41 to 50 of about 348,694 (266)
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Evaluation of the OpTest Fiber Quality Analyzer for Quantifying Cotton and Rayon Microfibers
FibersMicrofibers are small fiber particles that separate from larger textiles through wear abrasion or home laundering. Pervasive accumulation of synthetic microfibers in the environment is motivating efforts to quantify them, and to gain a better ...
Michael Santiago Cintron +1 more
doaj +1 more source
Borosilicate Based Hollow-Core Optical Fibers
Fibers, 2019 We discuss the fabrication of hollow-core optical fibers made of borosilicate glass. We show that, despite the high attenuation of the glass relative to silica, the fiber optical losses can be of the same order of magnitude of those obtained by using ...
Walter Belardi, Pier John Sazio
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Düzce University Faculty of Forestry Journal of Forestry, 2013 Bu çalışmada titrek kavak (Populus tremula L.) ağacının kimyasal analizleri ve lif yapısı incelenmiştir. Titrek kavak odunu, Bartın orman işletme müdürlüğüne bağlı Arıt şefliğinden temin edilmiştir.
Mehmet Onurhan Gücüş +1 more
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Turkish Journal of ForestryFiberboards, when disposed of at the end of their service life, cause some significant environmental issues such as air pollution. The recycling of fiberboards is the most effective solution to these problems; however, it has not yet found a widespread ...
Çağrı Olgun
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source