Results 61 to 70 of about 583,576 (336)

Un th\'eor\`eme du support pour la fibration de Hitchin [PDF]

open access: yes, 2014
The main tool in Ng\^o Bao Ch\^au's proof of the Langlands-Shelstad fundamental lemma, is a theorem on the support of the relative cohomology of the elliptic part of the Hitchin fibration.
Pierre-Henri Chaudouard, G. Laumon
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Theories of class F and anomalies

open access: yesJournal of High Energy Physics, 2018
We consider the 6d (2, 0) theory on a fibration by genus g curves, and dimensionally reduce along the fiber to 4d theories with duality defects. This generalizes class S theories, for which the fibration is trivial.
Craig Lawrie   +2 more
doaj   +1 more source

On the fibration method for zero-cycles and rational points [PDF]

open access: yes, 2014
Conjectures on the existence of zero-cycles on arbitrary smooth projective varieties over number fields were proposed by Colliot-Th\'el\`ene, Sansuc, Kato and Saito in the 1980's.
Yonatan Harpaz, Olivier Wittenberg
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gross fibration, SYZ mirror symmetry, and open Gromov-Witten invariants for toric Calabi-Yau orbifolds [PDF]

open access: yes, 2016
Given a toric Calabi-Yau orbifold X, we define and study a non-toric Lagrangian torus fibration on X, which we call the Gross fibration. We apply the SYZ recipe to a suitable modification of the Gross fibration of X to construct an instanton-corrected ...
Chan, Kwokwai   +3 more
core  

A TWISTED HOMOLOGY FIBRATION CRITERION AND THE TWISTED GROUP-COMPLETION THEOREM [PDF]

open access: yes, 2014
The purpose of this note is to clarify some details in McDuff and Segal's proof of the group-completion theorem and to generalize both this and the homology fibration criterion of McDuff to homology with twisted coefficients.
Jeremy Miller, Martin Palmer
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Generalized Tsen theorem and rationally connected Fano fibrations

open access: yes, 2001
We prove that a fibration X \to \Bbb P_1, the general fiber of which is a smooth Fano threefold, is rationally connected. The proof is based on a generalization of Tsen's classical theorem: a fibration X/C over a curve the general fiber of which is a ...
Campana, Frederic   +2 more
core   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas   +18 more
wiley   +1 more source

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