Results 41 to 50 of about 144,059 (268)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Development of Mechanical Extractor for Utilization of Pineapple Leaf Agro-Waste for Textile Application

Journal of Natural Fibers
In Indian subcontinent, pineapple (Ananas Comosus) leaves are left unused after fruits are harvested resulting in a waste of natural resources that contain textile-graded fibers.
Laxmi Kanta Nayak, Nageshkumar T, Prateek Shrivastava, Manisha Jagadale, Haokhothang Baite, Vidya Bhushan Shambhu, Manjunatha B. S.   +6 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

An extendable optical fibre probe survey meter for naturally occurring radioactive material (NORM) and other weak emitters

Scientific Reports, 2023
We have developed a radioluminescence-based survey meter for use in industries in which there is involvement in naturally occurring radioactive material (NORM), also in support of those needing to detect other weak emitters of radiation.
H. T. Zubair, D. A. Bradley, M. D. Khairina, Adebiyi Oresegun, A. Basaif, J. Othman, R. Rifiat, F. Hamidi, L. Rahman, A. Ezzadeen, S. A. Ibrahim, S. Mansor, M. Alkhorayef, H. A. Abdul-Rashid   +13 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Low-Cost Microcontroller-Enabled Embedded System for Assessing Jute Retting Water Quality Parameter

Journal of Natural Fibers
Quality of jute fiber depends to a very great extent on the quality of water used for retting. Efficient assessment of water quality is crucial to enable decision-makers to interpret this information and execute necessary management practices. Hence, the
Prateek Shrivastava, Deb Prasad Ray, Aishani Chowdhury, Nageshkumar T, Manisha Jagadale, V. B. Shambhu, Nilimesh Mridha, D. B. Shakyawar   +7 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

A novel sensor-based digital instrument for assessment of quality of fibre extracted from banana pseudostem

Heliyon
Banana (Musa paradisiaca) farming generates huge quantities of biomass, all of which goes to waste due to the non-availability of suitable technology for its commercial application.
Deb Prasad Ray, Prateek Shrivastava, Rakesh Kumar Ghosh, Manik Bhowmick, D.B. Shakyawar, Ipsita Das, Gunasindhu Sardar, Jayanta Mondal, S.C. Saha, Gautam Roy   +9 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source