Results 51 to 60 of about 320,879 (318)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Temperature and strain discrimination using a single tilted fibre Bragg grating [PDF]

, 2007
A fibre optic sensor capable of discriminating between temperature and strain, using a single fibre Bragg grating, is presented. The technique exploits the core–cladding mode coupling of a tilted fibre Bragg grating (TFBG). The core and cladding modes
Tatam, Ralph P., Chehura, Edmon, James, Stephen W.   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Fibre DFB lasers in a 4x10 Gbit/s WDM link with a single sinc-sampled fibre grating dispersion compensator

, 1998
WDM transmission and dispersion compensation at 40 Gbit/s over 200 km standard fibre is demonstrated on a 100 GHz grid using four high power single-polarisation single-sided output DFB fibre laser based transmitters and a single 4 channel WDM chirped ...
Laming, R.I., Ibsen, M., Fu, A., Geiger, H.   +3 more
core   +1 more source

Development of Mechanical Extractor for Utilization of Pineapple Leaf Agro-Waste for Textile Application

Journal of Natural Fibers
In Indian subcontinent, pineapple (Ananas Comosus) leaves are left unused after fruits are harvested resulting in a waste of natural resources that contain textile-graded fibers.
Laxmi Kanta Nayak, Nageshkumar T, Prateek Shrivastava, Manisha Jagadale, Haokhothang Baite, Vidya Bhushan Shambhu, Manjunatha B. S.   +6 more
doaj   +1 more source

An extendable optical fibre probe survey meter for naturally occurring radioactive material (NORM) and other weak emitters

Scientific Reports, 2023
We have developed a radioluminescence-based survey meter for use in industries in which there is involvement in naturally occurring radioactive material (NORM), also in support of those needing to detect other weak emitters of radiation.
H. T. Zubair, D. A. Bradley, M. D. Khairina, Adebiyi Oresegun, A. Basaif, J. Othman, R. Rifiat, F. Hamidi, L. Rahman, A. Ezzadeen, S. A. Ibrahim, S. Mansor, M. Alkhorayef, H. A. Abdul-Rashid   +13 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Interface strength in glass fibre-polypropylene measured using the fibre pull-out and microdebond methods

, 2009
Interface strength in glass fibre-polypropylene was measured using both fibre pull-out and microdebond methods. Excellent compatibility between two methods was obtained. The data from microdebond test could be divided into two groups according to whether
Thomason, James, Yang, Liu, Yang, L., Thomason, J.L.   +3 more
core   +1 more source

Characterization of the response of fibre Bragg gratings fabricated in stress and geometrically induced high birefringence fibres to temperature and transverse load. [PDF]

, 2004
The transverse load and temperature sensitivities of fibre Bragg gratings (FBGs) fabricated in a range of commercially available stress and geometrically induced high birefringent (HiBi) fibres have been experimentally investigated.
Staines, Stephen E., Ye, C. C., Ye, Chen-Chun, James, S. W., Tatam, Ralph P., Tatam, R. P., Chehura, Edmon, James, Stephen W., Staines, S. E., Chehura, E., 叶陈春   +10 more
core   +1 more source