Results 31 to 40 of about 144,937 (267)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Exploring the genomic landscape of mites and harnessing MITE insertion polymorphism markers in jute (Corchorus sp.)

Scientific Reports
Jute, a sustainable bast fibre crop from the Malvaceae family, has significant industrial applications and ecological benefits, making it an important focus of recent scientific research.
Rakesh Bhowmick, Kumar Nishant Chourasia, Jitendra Kumar Meena, Kanti Meena, Jiban Mitra, Gouranga Kar, R. Thribhuvan   +6 more
doaj   +1 more source

The deep sea is a major sink for microplastic debris [PDF]

Royal Society Open Science, 2014
Marine debris, mostly consisting of plastic, is a global problem, negatively impacting wildlife, tourism and shipping. However, despite the durability of plastic, and the exponential increase in its production, monitoring data show limited evidence of ...
Lucy C. Woodall, Anna Sanchez-Vidal, Miquel Canals, Gordon L.J. Paterson, Rachel Coppock, Victoria Sleight, Antonio Calafat, Alex D. Rogers, Bhavani E. Narayanaswamy, Richard C. Thompson   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

System productivity, profitability and resource use efficiency of jute (Corchorus olitorius) based cropping systems in the eastern Indo-gangetic plain

The Indian Journal of Agricultural Sciences, 2014
The study was conducted to investigate productivity, profitability and energy use of different jute (Corchorus olitorius L.) based cropping systems in the eastern India on farmers' fields during 2009-12. Nine cropping systems, viz.
MUKESH KUMAR, S R SINGH, S K JHA, SHAMNA A, SONALI P MAZUMDAR, AMARPREET SINGH, D K KUNDU, B S MAHAPATRA   +7 more
doaj   +1 more source

Laboratory evaluation of combined effect of jute fibres and rejuvenators on some performance characteristics of asphalt mixture containing reclaimed asphalt

Roads and Bridges, 2023
The use of reclaimed asphalt (RA) in asphalt concrete mixtures have achieved economic and environmental benefits and it is important when we want to get in line with sustainable development and circular economy.
Peter Gallo, Majda Belhaj, Jan Valentin, Pavla Vackova   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source