Results 1 to 10 of about 5,538,595 (306)
Conjugated Polymeric Materials in Biological Imaging and Cancer Therapy
Conjugated polymers (CPs) have attracted much attention in the fields of chemistry, medicine, life science, and material science. Researchers have carried out a series of innovative researches and have made significant research progress regarding the ...
Qinbin Zheng +7 more
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Evidence indicates that patients with Alzheimer’s dementia (AD) show signs of copper (Cu) dyshomeostasis. This study aimed at evaluating the potential of Cu dysregulation as an AD susceptibility factor.
Rosanna Squitti +13 more
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Loss of Neuroprotective Factors in Neurodegenerative Dementias: The End or the Starting Point?
Recent clinical, genetic and biochemical experimental evidences highlight the existence of common molecular pathways underlying neurodegenerative diseases.
Luisa Benussi +3 more
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Prodromal frontotemporal dementia: clinical features and predictors of progression
Background The prodromal phase of frontotemporal dementia (FTD) is still not well characterized, and conversion rates to dementia and predictors of progression at 1-year follow-up are currently unknown.
Alberto Benussi +9 more
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Allogeneic transplantation (HSCT) is an effective curative therapy for high risk acute myeloid leukemia (AML) which account for 38% of the transplants in Europe (1). Prior to HSCT, a conditioning or preparative regimen is administered.
Arnon Nagler
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High-Throughput Sequencing Strategy for Microsatellite Genotyping Using Neotropical Fish as a Model
Genetic diversity and population studies are essential for conservation and wildlife management programs. However, monitoring requires the analysis of multiple loci from many samples. These processes can be laborious and expensive.
Juliana S. M. Pimentel +9 more
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Background A consensus protocol for genetic counselling and testing of familial dementia, the Italian Dominantly Inherited Alzheimer’s and Frontotemporal Network (IT-DIAfN) protocol, has been developed in Italy by a network of expert dementia centres ...
Anna Mega +9 more
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Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease
One of the earliest pathological features characterizing Alzheimer’s disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating this loss of neuronal connectivity, the contribution of Rho-GTPases is of particular interest.
Mirta Borin +15 more
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Background The Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ1–42, t-tau, and p-tau181 overlap with other diseases. New tau modifications or epitopes, such as the non-phosphorylated tau fraction (p-taurel), may improve differential ...
Joery Goossens +15 more
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Peckia is one of the most important genera in the Sarcophagidae family of flesh flies. This genus is distributed in Brazil and Latin America, and its species can be used to estimate the Post Mortem Interval (PMI) in forensic investigations.
Susanne Faccin +5 more
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