Results 21 to 30 of about 1,319,694 (261)

Clinical and molecular markers in COPD

Pulmonology, 2018
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease, and there is a clinical need for validated markers and biomarkers that can contribute to the assessment of patients, risk prediction, treatment guidance, and assessment of response.
Gonçalves, I, Guimarães, MJ, van Zeller, M, Menezes, F, Moita, J, Simão, P   +5 more
openaire   +5 more sources

Genetic counselling and testing for inherited dementia: single-centre evaluation of the consensus Italian DIAfN protocol

Alzheimer’s Research & Therapy, 2020
Background A consensus protocol for genetic counselling and testing of familial dementia, the Italian Dominantly Inherited Alzheimer’s and Frontotemporal Network (IT-DIAfN) protocol, has been developed in Italy by a network of expert dementia centres ...
Anna Mega, Samantha Galluzzi, Cristian Bonvicini, Silvia Fostinelli, Massimo Gennarelli, Cristina Geroldi, Orazio Zanetti, Luisa Benussi, Emilio Di Maria, Giovanni B. Frisoni   +9 more
doaj   +1 more source

Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease

Acta Neuropathologica Communications, 2018
One of the earliest pathological features characterizing Alzheimer’s disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating this loss of neuronal connectivity, the contribution of Rho-GTPases is of particular interest.
Mirta Borin, Claudia Saraceno, Marcella Catania, Erika Lorenzetto, Valeria Pontelli, Anna Paterlini, Silvia Fostinelli, Anna Avesani, Giuseppe Di Fede, Gianluigi Zanusso, Luisa Benussi, Giuliano Binetti, Simone Zorzan, Roberta Ghidoni, Mario Buffelli, Silvia Bolognin   +15 more
doaj   +1 more source

No added diagnostic value of non-phosphorylated tau fraction (p-taurel) in CSF as a biomarker for differential dementia diagnosis

Alzheimer’s Research & Therapy, 2017
Background The Alzheimer’s disease (AD) cerebrospinal fluid (CSF) biomarkers Aβ1–42, t-tau, and p-tau181 overlap with other diseases. New tau modifications or epitopes, such as the non-phosphorylated tau fraction (p-taurel), may improve differential ...
Joery Goossens, Maria Bjerke, Hanne Struyfs, Ellis Niemantsverdriet, Charisse Somers, Tobi Van den Bossche, Sara Van Mossevelde, Bart De Vil, Anne Sieben, Jean-Jacques Martin, Patrick Cras, Johan Goeman, Peter Paul De Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs   +15 more
doaj   +1 more source

Complete mitochondrial genomes from three species of the genus Peckia (Sarcophagidae) with forensic entomology interest

Mitochondrial DNA. Part B. Resources, 2019
Peckia is one of the most important genera in the Sarcophagidae family of flesh flies. This genus is distributed in Brazil and Latin America, and its species can be used to estimate the Post Mortem Interval (PMI) in forensic investigations.
Susanne Faccin, Anderson Oliveira do Carmo, Patrícia J. Thyssen, Deodália Dias, Maria Teresa Rebelo, Evanguedes Kalapothakis   +5 more
doaj   +1 more source

FeCoNi Sulfides Derived From In situ Sulfurization of Precursor Oxides as Oxygen Evolution Reaction Catalyst

Frontiers in Chemistry, 2020
It is highly promising to design and develop efficient and economical electrocatalysts for oxygen evolution reaction (OER) in alkaline solution. In this work, we prepare FeCoNi sulfide composites (including FeS, Co3S4, and Ni3S4) derived from in situ ...
Wanqing Teng, Mengtian Huo, Zhaomei Sun, Wenrong Yang, Xiangjiang Zheng, Caifeng Ding, Shusheng Zhang   +6 more
doaj   +1 more source

A polyphasic approach to the characterization of potential silver-nanoparticles–producing and non-producing isolates of Alternaria species and antifungal activity against mycotoxigenic fungi

Biotechnology & Biotechnological Equipment, 2021
A polyphasic approach consisting of physical, chemical and molecular characterization was applied to three Alternaria species, A. alternata, A. chlamydospora and A.
Mayasar Ibrahim Al-Zaban, Mohamed Abobakr Mahmoud, Maha Abdullah Alharbi   +2 more
doaj   +1 more source

Transferability of SSR markers from Eugenia uniflora L. to Myrtaceae species of the Atlantic Forest

Acta Botânica Brasílica, 2023
The Myrtaceae family is home to several species of economic and ecological importance, but many are in areas of constant environmental degradation, demanding studies aiming at the conservation status evaluation or other characteristics of interest.
Dalvan Carlos Beise, Luana Oliveira de Oliveira, Daniele Damian dos Santos, Rafael Plá Matielo Lemos, Cristiane D’ Oliveira Matielo, Renata Machado Castro, Valdir Marcos Stefenon   +6 more
doaj   +1 more source

Genetic diversity of Brazilian Bacillus thuringiensis isolates with toxicity against Aedes aegypti (Diptera: Culicidae)

Scientific Reports, 2022
Bacillus thuringiensis (Bt) isolates native to Maranhão (BtMA) that are highly toxic to Aedes aegypti larvae and seven standard subspecies of Bt were analyzed for genetic diversity using the rep-PRC technique with BOX, ERIC, REP, MB1, and GTG5 markers ...
Geysla da Costa Fernandes, Dalton Kaynnan de Prado Costa, Nayanne Santos de Oliveira, Emanuelle Cristine Pereira de Sousa, Déborah Heloísa Bittencourt Machado, Ricardo Antonio Polanczyk, Herbert Álvaro Abreu de Siqueira, Maria Cleoneide da Silva   +7 more
doaj   +1 more source

Amyloid-β1–43 cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations

Alzheimer’s Research & Therapy, 2020
Background Alzheimer’s disease (AD) mutations in amyloid precursor protein (APP) and presenilins (PSENs) could potentially lead to the production of longer amyloidogenic Aβ peptides. Amongst these, Aβ1–43 is more prone to aggregation and has higher toxic
Federica Perrone, Maria Bjerke, Elisabeth Hens, Anne Sieben, Maarten Timmers, Arne De Roeck, Rik Vandenberghe, Kristel Sleegers, Jean-Jacques Martin, Peter P. De Deyn, Sebastiaan Engelborghs, Julie van der Zee, Christine Van Broeckhoven, Rita Cacace, on behalf of the BELNEU Consortium   +14 more
doaj   +1 more source