Results 51 to 60 of about 127,967 (338)
Hierarchical nanomechanics of collagen microfibrils [PDF]
, 2010 Collagen constitutes one third of the human proteome, providing mechanical stability, elasticity and strength to connective tissues. Collagen is also the dominating material in the extracellular matrix (ECM) and is thus crucial for cell differentiation ...
Alberto Redaelli +3 more
core +2 more sources
Short dynamic fibrils in sunspot chromospheres
, 2013 Sunspot chromospheres display vigorous oscillatory signature when observed in chromospheric diagnostics like the strong Ca II lines and H-alpha. New high-resolution sunspot observations from the Swedish 1-m Solar Telescope show the ubiquitous presence of
Rodriguez, Jaime de la Cruz +1 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Effects of chondroitin sulfate B on the reconstitution of collagen fibrils
Nihon Kikai Gakkai ronbunshu, 2017 Collagen fibrils were reconstituted in vitro from type I collagen solution. The reconstituted collagen fibrils and chondroitin sulfate B were deposited alternately.
Noritaka YAMAMOTO, Ken SASAKI
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2020 Human aging is accompanied by a relevant increase in age-associated chronic pathologies, including neurodegenerative and metabolic diseases. The appearance and evolution of numerous neurodegenerative diseases is paralleled by the appearance of ...
Jose A. del Rio +8 more
doaj +1 more source
The structure and performance of collagen biomaterials : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Engineering, Massey University, Palmerston North, New Zealand [PDF]
, 2016 Type I collagen materials are used in a wide range of industrial applications. Some examples include leather for shoes and upholstery, acellular dermal matrix (ADM) materials for surgical applications, and bovine pericardium for the fabrication of ...
Wells, Hannah
core
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
PLoS ONE, 2021 Assembly of the extracellular matrix protein fibronectin (FN) into insoluble, viscoelastic fibrils is a critical step during embryonic development and wound healing; misregulation of FN fibril assembly has been implicated in many diseases, including ...
Seth H Weinberg +2 more
doaj +1 more source
The relationship between amyloid structure and cytotoxicity [PDF]
, 2014 Self-assembly of proteins and peptides into amyloid structures has been the subject of intense and focused research due to their association with neurodegenerative, age-related human diseases and transmissible prion diseases in humans and mammals. Of the
Marchante, Ricardo +3 more
core +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source