Results 71 to 80 of about 601,314 (362)

Glycemic control is associated with atrial structural remodeling in patients with type 2 diabetes

BMC Cardiovascular Disorders, 2019
Background Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and glycemic control affect the pathogenesis of AF has not been sufficiently investigated ...
Qing Wang, Jing Wang, Pei Wang, Liaoyuan Wang, Lanting Jia, Xinyu Ling, Wang Xi, Jie Min, Hua Shen, Jian Xiao, Jinxiang Yuan, Zhinong Wang   +11 more
doaj   +1 more source

Sensing Cells-Peptide Hydrogel Interaction In Situ via Scanning Ion Conductance Microscopy

Cells, 2022
Peptide-based hydrogels were shown to serve as good matrices for 3D cell culture and to be applied in the field of regenerative medicine. The study of the cell-matrix interaction is important for the understanding of cell attachment, proliferation, and ...
Tatiana N. Tikhonova, Vasilii S. Kolmogorov, Roman V. Timoshenko, Alexander N. Vaneev, Dana Cohen-Gerassi, Liubov A. Osminkina, Petr V. Gorelkin, Alexander S. Erofeev, Nikolay N. Sysoev, Lihi Adler-Abramovich, Evgeny A. Shirshin   +10 more
doaj   +1 more source

Nucleation of amyloid fibrils [PDF]

J. Chem. Phys. 132, 215101 (2010), 2010
We consider nucleation of amyloid fibrils in the case when the process occurs by the mechanism of direct polymerization of practically fully extended protein segments, i.e. beta-strands, into beta-sheets. Applying the classical nucleation theory, we derive a general expression for the work to form a nanosized amyloid fibril (protofilament) constituted ...
arxiv   +1 more source

Atrial Fibrillation and Myocardial Infarction: A Systematic Review and Appraisal of Pathophysiologic Mechanisms [PDF]

, 2016
A growing body of evidence suggests that atrial fibrillation (AF) is associated with myocardial infarction (MI). However, incidence and management of MI in AF is still undefined. METHODS AND RESULTS: We searched MEDLINE via PubMed and Cochrane database
PASTORI, DANIELE, PIGNATELLI, Pasquale, Soliman, Elsayed Z, VIOLI, Francesco   +3 more
core   +1 more source

Atrial fibrillation and microRNAs [PDF]

Frontiers in Physiology, 2014
Atrial fibrillation (AF) is the most common sustained arrhythmia, especially in the elderly, and has a significant genetic component. Recently, several independent investigators have demonstrated a functional role for small non-coding RNAs (microRNAs) in the pathophysiology of this cardiac arrhythmia.
Santulli, Gaetano, IACCARINO, Guido, De Luca, Nicola, Trimarco, Bruno, Condorelli, Gianluigi   +4 more
openaire   +5 more sources

Native Lignin Migration and Clustering in Wood: Superhydrophobic, Antimold, and Tribonegative Layers for Rain‐Driven Electrification

Advanced Functional Materials, EarlyView.
This study proposes a sustainable solution for rainwater‐driven energy harvesting by harnessing the intrinsic properties of lignin in wood. The first demonstration of an all‐wood tribonegative material for liquid–solid triboelectric nanogenerators is presented, eliminating the need for fluorine‐containing polymers and functional additives. Abstract The
Xuetong Shi, Ran Bi, Xin Shu, Peipei Wang, Yeedo Chun, Zhixiang Chen, Chris Zhou, Yi Lu, Orlando J. Rojas   +8 more
wiley   +1 more source

Cardioprotective effects of dantrolene in doxorubicin-induced cardiomyopathy in mice

Heart Rhythm O2, 2021
Background: Doxorubicin (Dox) is a potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. Intracellular calcium dysregulation has been reported to be involved in doxorubicin-induced cardiomyopathy (DICM).
Mohammed Ali Azam, MBBS, PhD, Praloy Chakraborty, MD, Mahmoud M. Bokhari, MBBS, Keith Dadson, PhD, Beibei Du, MD, PhD, Stéphane Massé, MASc, Daoyuan Si, MD, PhD, Ahmed Niri, BEng, Arjun K. Aggarwal, Patrick F.H. Lai, MSc, Sheila Riazi, MD, MSc, Filio Billia, MD, PhD, Kumaraswamy Nanthakumar, MD   +12 more
doaj  

Nanoparticles With a Specific Size and Surface Charge Promote Disruption of the Secondary Structure and Amyloid-Like Fibrillation of Human Insulin Under Physiological Conditions

Frontiers in Chemistry, 2019
Nanoparticles attract much interest as fluorescent labels for diagnostic and therapeutic tools, although their applications are often hindered by size- and shape-dependent cytotoxicity.
Alyona Sukhanova, Alyona Sukhanova, Simon Poly, Svetlana Bozrova, Éléonore Lambert, Maxime Ewald, Alexander Karaulov, Michael Molinari, Igor Nabiev, Igor Nabiev   +9 more
doaj   +1 more source

Characteristics of Cellulose Nanofibrils from Transgenic Trees with Reduced Expression of Cellulose Synthase Interacting 1

Nanomaterials, 2022
Cellulose nanofibrils can be derived from the native load-bearing cellulose microfibrils in wood. These microfibrils are synthesized by a cellulose synthase enzyme complex that resides in the plasma membrane of developing wood cells.
Simon Jonasson, Anne Bünder, Linn Berglund, Totte Niittylä, Kristiina Oksman   +4 more
doaj   +1 more source

What drives amyloid molecules to assemble into oligomers and fibrils? [PDF]

, 2010
We develop a general theory for three states of equilibrium of amyloid peptides: the monomer, oligomer, and fibril. We assume that the oligomeric state is a disordered micelle-like collection of a few peptide chains held together loosely by hydrophobic interactions into a spherical hydrophobic core.
arxiv   +1 more source