Results 11 to 20 of about 15,376 (205)

The Fibrillin-1/VEGFR2/STAT2 signaling axis promotes chemoresistance via modulating glycolysis and angiogenesis in ovarian cancer organoids and cells. [PDF]

Cancer Commun (Lond), 2022
Wang Z, Chen W, Zuo L, Xu M, Wu Y, Huang J, Zhang X, Li Y, Wang J, Chen J, Wang H, Sun H.   +11 more
europepmc   +2 more sources

Asprosin, a C-Terminal Cleavage Product of Fibrillin 1 Encoded by the FBN1 Gene, in Health and Disease. [PDF]

Mol Syndromol, 2022
Ovali MA, Bozgeyik I.
europepmc   +3 more sources

Myelofibrosis progression grading based on type I and type III collagen and fibrillin 1 expression boosted by whole slide image analysis. [PDF]

Histopathology, 2023
Szekely T, Wichmann B, Maros ME, Csizmadia A, Bodor C, Timar B, Krenacs T.   +6 more
europepmc   +2 more sources

Marfan syndrome variation of the POGLUT2 and POGLUT3 consensus sequence can produce aberrant fibrillin-1 O-glucosylation. [PDF]

J Biol Chem
Kegley NR, Ito A, Williamson DB, McArdle CC, Haltiwanger RS.   +4 more
europepmc   +2 more sources

Macromolecular crowding enhances fibrillin-1 deposition in the extracellular matrix [PDF]

European Cells & Materials, 2022
Biochemical and biophysical factors need consideration when modelling in vivo cellular behaviour using in vitro cell culture systems. One underappreciated factor is the high concentration of macromolecules present in vivo, which is typically not ...
B Satz-Jacobowitz, N Taye, SZ Karoulias, D Hubmacher   +3 more
doaj   +1 more source

New Studies of the Aberrant Alterations in Fibrillin-1 Methylation During Colorectal Cancer Development. [PDF]

Front Oncol, 2022
Lv L, Ma J, Wu L, Zhang C, Wang Y, Wang G.   +5 more
europepmc   +3 more sources

Significance of Fibrillin-1, Filamin A, MMP2 and SOX9 in Mitral Valve Pathology. [PDF]

Int J Mol Sci
Opris CE, Suciu H, Jung I, Flamand S, Harpa MM, Opris CI, Popa C, Kovacs Z, Gurzu S.   +8 more
europepmc   +3 more sources

Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

eLife, 2022
The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known.
Timothy J Mead, Daniel R Martin, Lauren W Wang, Stuart A Cain, Cagri Gulec, Elisabeth Cahill, Joseph Mauch, Dieter Reinhardt, Cecilia Lo, Clair Baldock, Suneel S Apte   +10 more
doaj   +1 more source

Circulating fibrillin fragment concentrations in patients with and without aortic pathology

JVS - Vascular Science, 2022
Objective: Fragments of fibrillin-1 and fibrillin-2 will be detectable in the plasma of patients with aortic dissections and aneurysms. We sought to determine whether the plasma fibrillin fragment levels (PFFLs) differ between patients with thoracic ...
Eric J. Carlson, PhD, Megan Rushkin, BA, Derek Darby, BA, Trisha Chau, BS, Renee L. Shirley, PhD, Jeff S. King, PhD, Khanh Nguyen, MD, Gregory J. Landry, MD, Gregory L. Moneta, MD, Cherrie Abraham, MD, Lynn Y. Sakai, PhD, Amir F. Azarbal, MD   +11 more
doaj   +1 more source

Pathogenic variants affecting the TB5 domain of the fibrillin-1 protein: not only in geleophysic/acromicric dysplasias but also in Marfan syndrome. [PDF]

J Med Genet
Arnaud P, Mougin Z, Baujat G, Drouin-Garraud V, El Chehadeh S, Gouya L, Odent S, Jondeau G, Boileau C, Hanna N, Le Goff C.   +10 more
europepmc   +3 more sources