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Immobilisation of a fibrillin-1 fragment enhances the biocompatibility of PTFE
Colloids and Surfaces B: Biointerfaces, 2014Current vascular biomaterials exhibit poor biocompatibility characterised by failure to promote endothelialisation, predisposition to neoinitmal hyperplasia and excessive thrombogenicity. Fibrillin-1, a major constituent of microfibrils is associated with elastic fibres in the arterial wall.
Louise L. Dunn +12 more
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PARTIAL CLONING AND SEQUENCING OF CHICK FIBRILLIN-1 cDNA
In Vitro Cellular & Developmental Biology - Animal, 2000The recent identification of numerous matrix genes and gene products has allowed a detailed examination of their roles in development. Two of these extracellular matrix proteins, fibrillin-1 and fibrillin-2, are components of the elastin-associated microfibrils.
Guimei Zhou +4 more
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Abnormal Hepatic Expression of Fibrillin-1 in Children With Cholestasis
The American Journal of Surgical Pathology, 2002Fibrillin-1, one of the main constituents of microfibrils, is present in normal adult liver and overexpressed in fibrotic area around cirrhotic nodules and hepatocellular carcinoma. In this work fibrillin-1 expression was studied by immunohistochemistry in liver samples from children with various cholestatic diseases corresponding to paucity of ...
Thierry Lamireau +6 more
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Fibrillin-1 Protein in Tight Skin Mice and Scleroderma
Clinical Reviews in Allergy & Immunology, 2000Scleroderma (SSc) is a complex and clinically heterogenous disease of unknown origin, in which both genetic and environmental factors appear to be implicated. In addition to skin, other internal organs, including lung, heart, intestine, and kidney, can be affected.
Constantin A. Bona, Shinichiro Saito
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Biochemical Journal, 2016
The 10-12 nm diameter microfibrils of the extracellular matrix (ECM) impart both structural and regulatory properties to load-bearing connective tissues.
S. Jensen, P. Handford
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The 10-12 nm diameter microfibrils of the extracellular matrix (ECM) impart both structural and regulatory properties to load-bearing connective tissues.
S. Jensen, P. Handford
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Fibrillin-1 regulates white adipose tissue development, homeostasis, and function.
Matrix Biology, 2022Muthu L. Muthu +4 more
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Fibrillin‐1 and elastin are differentially expressed in hypertrophic scars and keloids
Wound Repair and Regeneration, 2004Hypertrophic scars and keloids are two forms of excessive cutaneous scarring. Considering the importance of extracellular matrix elements in tissue repair, a morphological and quantitative analysis of the elastic system components (fibrillin‐1 and elastin) was performed in normal skin, normal scars, hypertrophic scars, and keloids.
Alexis Desmoulière +4 more
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The Role of Fibrillin-1 in Eye Development and Disease
2018The ciliary zonule of the human eye consists of a circumferential array of fibers that connect the ocular lens to the nonpigmented ciliary epithelium (NPCE) located at the inner wall of the eye. Zonular fibers consist of bundles of beaded filaments called microfibrils.
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A potential role of fibrillin-1 (FBN1) mRNA and asprosin in follicular development in water buffalo.
Theriogenology, 2021E. R. Maylem +5 more
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Cysteine mutations of fibrillin-1 in marfan syndrome [PDF]
Biochemical Society Transactions, 2002 Penny A. Handford +3 more
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