Role of fibrilins in human cancer: A narrative review [PDF]
Health Science Reports, 2023 Background Fibrillin is one of the extracellular matrix glycoproteins and participates in forming microfibrils found in many connective tissues. The microfibrils enable the elasticity and stretching properties of the ligaments and support connective ...
Mahsa Mahdizadehi +3 more
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Case Report: A Novel Homozygous Missense Variant of FBN3 Supporting It Is a New Candidate Gene Causative of a Bardet–Biedl Syndrome–Like Phenotype [PDF]
Frontiers in Genetics, 2022 Fibrillin proteins are extracellular matrix glycoproteins assembling into microfibrils. FBN1, FBN2, and FBN3 encode the human fibrillins and mutations in FBN1 and FBN2 cause connective tissue disorders called fibrillinopathies, affecting cardiovascular ...
Maria Luce Genovesi +8 more
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The ADAMTS family: from extracellular matrix proteases to orchestrators of fibrosis [PDF]
Cell Communication and SignalingFibrosis, a pathological process defined by excessive extracellular matrix (ECM) accumulation, contributes significantly to chronic organ failure worldwide.
Yang Yuan +4 more
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Arabidopsis thaliana Fibrillin 3a binds saturated fatty acids of chloroplast membranes [PDF]
Plant Signaling & BehaviorFibrillins (FBNs) are conserved plastid lipid–associated proteins involved in lipid storage, stress adaptation and plastid ultrastructure. While several Arabidopsis thaliana FBNs have been functionally characterized, the biochemical properties of the ...
Andrés Herrera-Tequia +2 more
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Characterization and Functional Analysis of the FBN Gene Family in Cotton: Insights into Fiber Development [PDF]
BiologyFibrillins (FBNs) are indispensable for plant growth and development, orchestrating multiple physiological processes. However, the precise functional role of FBNs in cotton fiber development remains uncharacterized.
Sunhui Yan +5 more
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The Evolution of Extracellular Fibrillins and Their Functional Domains
PLoS ONE, 2012 Fibrillins constitute the major backbone of multifunctional microfibrils in elastic and non-elastic extracellular matrices, and are known to interact with several binding partners including tropoelastin and integrins.
Wayne S Sossin, Dieter P Reinhardt
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Fibrillin gene family and its role in plant growth, development, and abiotic stress [PDF]
Frontiers in Plant ScienceFibrillins (FBNs), highly conserved plastid lipid-associated proteins (PAPs), play a crucial role in plant physiology. These proteins, encoded by nuclear genes, are prevalent in the plastoglobules (PGs) of chloroplasts.
Ahmed H. El-Sappah +9 more
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OsFBN6 Enhances Brown Spot Disease Resistance in Rice [PDF]
PlantsBrown spot (BS) is caused by necrotrophs fungi Cochliobolus miyabeanus (C. miyabeanus) which affects rainfed and upland production in rice, resulting in significant losses in yield and grain quality.
Fang-Yuan Cao +6 more
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Defining the Extracellular Matrix of Rhabdomyosarcoma
Frontiers in Oncology, 2021 Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood with a propensity to metastasize. Current treatment for patients with RMS includes conventional systemic chemotherapy, radiation therapy, and surgical resection; nevertheless ...
Xiaolei Lian +17 more
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Aquaculture Reports, 2022 The razor clam, Sinonovacula constricta, must have acquired adaptive mechanisms to defense thermal pressure during evolution as it’s an eurythermal bivalve. However, the specific mechanisms remain unclear. To identify thermal responsive genes and unravel
Xianghui Kong +5 more
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