Results 61 to 70 of about 1,608 (150)

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, Volume 293, Issue 13, Page 3991-4013, July 2026.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

The fibrillinopathies: New insights with focus on the paradigm of opposing phenotypes for both FBN1 and FBN2. [PDF]

Hum Mutat, 2022
Peeters S, De Kinderen P, Meester JAN, Verstraeten A, Loeys BL.   +4 more
europepmc   +1 more source

Extracellular Matrix of Echinoderms. [PDF]

Mar Drugs, 2023
Dolmatov IY, Nizhnichenko VA.
europepmc   +1 more source

Systematic Disruption of Zebrafish Fibrillin Genes Identifies a Translational Zebrafish Model for Marfan Syndrome. [PDF]

JACC Basic Transl Sci
De Rycke K, Horvat M, Caboor L, Vermassen P, De Smet G, Lobbestael S, Santana Silva M, Steyaert W, Van Impe M, Segers P, De Backer J, Sips P.   +11 more
europepmc   +1 more source

Growth plate extracellular matrix defects and short stature in children. [PDF]

Ann Pediatr Endocrinol Metab, 2022
Saltarelli MA, Quarta A, Chiarelli F.
europepmc   +1 more source

Fibrillin-2 [PDF]

, 2020
openaire   +1 more source

The Diversity of Fibrillin Functions: Lessons from the Periodontal Ligament. [PDF]

Cells
Genot E, Al Tabosh T, Catros S, Alonso F, Le Nihouannen D.   +4 more
europepmc   +1 more source

Editorial: Cardiovascular calcification: disease mechanisms, clinical phenotypes and therapeutic strategies. [PDF]

Front Cardiovasc Med
Nollet L, Leftheriotis G, Vanakker OM.
europepmc   +1 more source