Results 71 to 80 of about 200,520 (286)

The relationship between amyloid structure and cytotoxicity [PDF]

, 2014
Self-assembly of proteins and peptides into amyloid structures has been the subject of intense and focused research due to their association with neurodegenerative, age-related human diseases and transmissible prion diseases in humans and mammals. Of the
Marchante, Ricardo, Marshall, Karen E, Serpell, Louise C, Xue, Wei-Feng   +3 more
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Highly rigid & transparent supramolecular fibrils of tyrosine

Nano Select, 2022
Various peptides and amino acids can self‐assemble into fibrils in a solution environment both in vivo and in vitro. These fibrils can aggregate as amyloids in the organs of individuals with certain genetic mutations, and can also be assembled in‐vitro ...
Ramesh Y. Adhikari, Jeiko J. Pujols
doaj   +1 more source

Fibrillisation of hydrophobically modified amyloid peptide fragments in an organic solvent [PDF]

, 2007
The self-assembly of a hydrophobically modified fragment of the amyloid beta(A beta) peptide has been studied in methanol. The peptide FFKLVFF is based on A beta(16-20) extended at the N terminus by two phenylalanine residues.
Castelletto, Valeria, Hamley, Ian W., Krysmann, M.J.   +2 more
core   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Structure-based inhibitors of amyloid beta core suggest a common interface with tau. [PDF]

, 2019
Alzheimer's disease (AD) pathology is characterized by plaques of amyloid beta (Aβ) and neurofibrillary tangles of tau. Aβ aggregation is thought to occur at early stages of the disease, and ultimately gives way to the formation of tau tangles which ...
Bowler, Jeannette, Cascio, Duilio, Eisenberg, David S, Glabe, Charles G, Gonen, Tamir, Griner, Sarah L, Murray, Kevin A, Philipp, Stephan, Rodriguez, Jose A, Sahay, Shruti, Sawaya, Michael R, Seidler, Paul, Sosna, Justyna, Yang, Tianxiao Peter   +13 more
core   +1 more source

MHD wave modes resolved in fine-scale chromospheric magnetic structures [PDF]

, 2015
Within the last decade, due to significant improvements in the spatial and temporal resolution of chromospheric data, magnetohydrodynamic (MHD) wave studies in this fascinating region of the Sun's atmosphere have risen to the forefront of solar physics ...
Jess, D. B., Verth, G.
core   +2 more sources

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

Advanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian, Frédéric Demoly, Mohammad Lakhi, Bernard Rolfe, Mahdi Bodaghi   +4 more
wiley   +1 more source

Enhancing Corrosion Resistance and Mechanical Strength of 3D‐Printed Iron Polylactic Acid for Marine Applications via Laser Surface Texturing

Advanced Engineering Materials, EarlyView.
Laser surface texturing significantly improves the corrosion resistance and mechanical strength of 3D‐printed iron polylactic acid (Ir‐PLA) for marine applications. Optimal laser parameters reduce corrosion by 80% and enhance tensile strength by 25% and ductility by 15%.
Mohammad Rezayat, Mojtaba Karamimoghadam, Mohammadreza Lalegani Dezaki, Ali Zolfagharian, Giuseppe Casalino, Antonio Mateo, Mahdi Bodaghi   +6 more
wiley   +1 more source

Toxic species in amyloid disorders: Oligomers or mature fibrils

Annals of Indian Academy of Neurology, 2015
Protein aggregation is the hallmark of several neurodegenerative disorders. These protein aggregation (fibrillization) disorders are also known as amyloid disorders. The mechanism of protein aggregation involves conformation switch of the native protein,
Meenakshi Verma, Abhishek Vats, Vibha Taneja   +2 more
doaj   +1 more source