Results 81 to 90 of about 1,767,987 (273)

Cross‐Scale Hierarchical Targeted Delivery System Based on Small‐Scale Magnetic Robots

Advanced Robotics Research, EarlyView.
This article reviews a cross‐scale hierarchical targeted delivery system that integrates magnetic continuum robots and magnetic microrobots. By combining rapid long‐range navigation with precise microscale targeting, the system overcomes key limitations of single‐scale approaches.
Junjian Zhou, Zhiqiang Chen, Yuanbiao Ma, Zhiqiang Tang, Qianqian Wang   +4 more
wiley   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

Advanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang, Yu Dong, Yongsheng Du, Rui Gao, Lin Zhang, Fei Tong   +5 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Fabrication of Artificial Nerve Conduits Used in a Long Nerve Gap: Current Reviews and Future Studies

Bioengineering
There are many commercially available artificial nerve conduits, used mostly to repair short gaps in sensory nerves. The stages of nerve regeneration in a nerve conduit are fibrin matrix formation between the nerve stumps joined to the conduit, capillary
Ryosuke Kakinoki, Yukiko Hara, Koichi Yoshimoto, Yukitoshi Kaizawa, Kazuhiko Hashimoto, Hiroki Tanaka, Takaya Kobayashi, Kazuhiro Ohtani, Takashi Noguchi, Ryosuke Ikeguchi, Masao Akagi, Koji Goto   +11 more
doaj   +1 more source

3D Microfluidic Bone Tumor Microenvironment Comprised of Hydroxyapatite/Fibrin Composite

Frontiers in Bioengineering and Biotechnology, 2019
Bone is one of the most common sites of cancer metastasis, as its fertile microenvironment attracts tumor cells. The unique mechanical properties of bone extracellular matrix (ECM), mainly composed of hydroxyapatite (HA) affect a number of cellular ...
Jungho Ahn, Jungho Ahn, Jungeun Lim, Jungeun Lim, Norhana Jusoh, Norhana Jusoh, Jungseub Lee, Tae-Eun Park, YongTae Kim, YongTae Kim, YongTae Kim, YongTae Kim, Jangho Kim, Noo Li Jeon, Noo Li Jeon, Noo Li Jeon, Noo Li Jeon   +16 more
doaj   +1 more source

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix [PDF]

, 2013
By binding growth factors (GFs), the ECM tightly regulates their activity. We recently reported that the heparin-binding domain II of fibronectin acts as a promiscuous high-affinity GF-binding domain. Here we hypothesized that fibrin, the provisional ECM
Martino, Mikael, Briquez, Priscilla, Lutolf, Matthias, Hubbell, Jeffrey Alan, Ranga, Adrian, Briquez PS, Martino MM, Ranga A, Lutolf MP, Hubbell JA   +9 more
core   +2 more sources

A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair

Advanced Science, EarlyView.
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang, Gong Cheng, Wenyong Fei, Qiuzhen Liang, Liang Zhang, Kegui Liu, Jihang Dai, Bo Cong, Xu Hu, Zhonglian Wu, Jialu Zhang, Jinlan Cui, Hang Yao, Dong‐An Wang, Jingcheng Wang, Tao Sun, Jiang Zheng   +16 more
wiley   +1 more source

Fibrin-rich environment drives catheter-associated UTIs by suppressing macrophage defenses

Nature Communications
Catheter-associated urinary tract infections (CAUTIs) pose severe clinical challenges, often leading to urosepsis and multidrug resistance. The wound-healing process triggered by catheter-induced bladder damage deposits fibrinogen and its polymerized ...
Armando M. Marrufo, Christopher Gager, Jonathan J. Molina, Marissa J. Andersen, Alyssa A. La Bella, Jessica J. Kean, Katelyn C. Fealy, Elizabeth R. Lucas, Ellsa Wongso, Tamanna Urmi, Kassandra Arias-Parbul, Railyn Webster, Peter V. Stuckey, Kurt N. Kohler, Deborah Donahue, Victoria A. Ploplis, Matthew J. Flick, Francis J. Castellino, Felipe H. Santiago-Tirado, Ana L. Flores-Mireles   +19 more
doaj   +1 more source

Enhancement of bone healing using non-glycosylated rhBMP-2 released from a fibrin matrix in dogs and cats. [PDF]

, 2005
OBJECTIVES: To test a non-glycosylated recombinant human bone morphogenetic protein-2 (ngly-rhBMP-2)/fibrin composite, which has been shown experimentally to enhance healing of bone defects in rodents, in a clinical case series of dogs and cats ...
Schense, J C, Schmoekel, H G, Seiler, Gabriela, Spreng, David, J. C. Schense, Schawalder, P, P. Schawalder, K. Hurter, Seiler, G, Weber, F. E., Spreng, D, H. G. Schmoekel, Hurter, K, Hubbell, J., G. Seiler, Schmökel, Hugo, Ryrz, U, Rytz, Ulrich, Weber, Franz E; https://orcid.org/, Hurter, K., U. Rytz, F. E. Weber, Schense, J. C., D. Spreng, Schawalder, Peter, J. Hubbell, Hubbell, J, Weber FE, Schense JC, Schmoekel HG, Hubbell J, Spreng D, Seiler G, Ryrz U, Hurter K, Schawalder P   +35 more
core   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source