Results 111 to 120 of about 1,925,371 (280)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

Comparison of glued platelet-rich fibrin membrane and noneugenol pack as periodontal dressings after gingival depigmentation

Journal of Indian Society of Periodontology
Periodontal surgery often necessitates the use of a periodontal dressing to protect the surgical site and facilitate healing. Commonly used dressings, such as noneugenol packs, offer some benefits but have significant drawbacks, including plaque ...
Megha Poojari, Monali Shah, Prasad Nadig
doaj   +1 more source

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Unfractionated Heparin and Low‐Molecular‐Weight Heparin in Sepsis: Anti‐Inflammatory and Anticoagulant Effects Versus No Anticoagulation—A Propensity Score‐Matched Analysis

Journal of Clinical Laboratory Analysis, EarlyView.
This propensity score‐matched study compared unfractionated heparin (UFH) and low‐molecular‐weight heparin (LMWH) in 1362 sepsis patients, finding that both significantly improved survival without increasing 90‐day bleeding risk. However, their therapeutic mechanisms differed: UFH demonstrated broader anti‐inflammatory effects by reducing IL‐6, IL‐8 ...
Peili Chen, Yi Yao, Bing Zhao, Yuan An, Jian Jiang, Li Ma, Enqiang Mao, Yihui Wang   +7 more
wiley   +1 more source

From Adhesion to Detachment: Strategies to Design Tissue‐Adhesive Hydrogels

Advanced NanoBiomed Research
The use of tissue adhesives dates to 1940s when surgical glues were introduced for wound closure applications. However, current clinically used tissue adhesives (fibrin and cyanoacrylate glues) have limited adhesion strength and biocompatibility issues ...
Minh Hieu Ho, Quinn van Hilst, Xiaolin Cui, Yogambha Ramaswamy, Tim Woodfield, Jelena Rnjak-Kovacina, Steven G. Wise, Khoon S. Lim   +7 more
doaj   +1 more source

Twenty‐four month clinical outcomes of modified coronally advanced tunnel technique with leukocyte‐ and platelet‐rich fibrin–functionalized porcine dermal matrix for single/multiple gingival recessions

Journal of Periodontology, EarlyView.
Abstract Background To report 24‐month clinical and 3D outcomes of single and multiple RT1 and RT2 gingival recessions treated with the modified coronally advanced tunnel (MCAT) technique and an L‐PRF‐functionalized porcine dermal matrix (PDM), as long‐term data on PDM in root coverage are scarce.
Erik Würflein, Katharina Herrmann, Anton Sculean, Kirstin Vach, Katja Nelson, Tobias Fretwurst, Gerhard Iglhaut, Florian Kernen   +7 more
wiley   +1 more source

Application of Fibrin Tissue Adhesive in Rhinology

Practica oto-rhino-laryngologica. Suppl., 1993
Nakamura, Haruhiko, Nishimura, Tadao, Morishima, Natsuki, Tokuda, Toshikazu, Yagisawa, Mikio   +4 more
openaire   +2 more sources

Role of Fibrin Tissue Adhesive in the ENT and Head & Neck Surgeries [PDF]

, 2016
The tissue adhesives have been used for various surgical procedures as a part of reinforcement of surgical sutures. In our study, conducted in the department of ENT, Stanley medical college, Chennai, we have observed and evaluated the effectiveness of ...
Devendiran, R
core  

The effect of leukocyte–platelet‐rich fibrin in periodontal surgery on clinical parameters and patient‐related outcome measures: A randomized, controlled, clinical study

Journal of Periodontology, EarlyView.
Abstract Background This prospective study aimed to assess the clinical outcomes and patient‐related outcome measures (PROMs) of open flap debridement (OFD) alone versus open flap debridement with leukocyte–platelet‐rich fibrin (L‐PRF). Methods Twenty‐one patients were enrolled into a split‐mouth randomized clinical trial.
Jackson S. Sides, Archontia Palaiologou, Brian L. Mealey, Stephan J. Haney, Kerri Font, Charles A. Powell   +5 more
wiley   +1 more source

Efficacy and safety of fibrin sealant for tissue adherence in facial rhytidectomy

, 2012
William D SpotnitzThe Surgical Therapeutic Advancement Center, Department of Surgery, University of Virginia Health System, Charlottesville, VA, USAAbstract: The purpose of this review is to clarify the present use of fibrin sealant in rhyditectomy ...
Spotnitz WD
core