Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis [PDF]
Immobilization of bioactive peptide sequences on CoCr surfaces is an effective route to improve endothelialization, which is of great interest for cardiovascular stents. In this work, we explored the effect of physical and covalent immoblization of RGDS,
Castellanos, Maria Isabel+8 more
core +3 more sources
The Role of Fibrin Tissue Adhesives in Flap Necrosis in Rats
Flap necrosis is an important issue in surgery, and fibrin tissue adhesives, due to beneficial properties in preventing flap necrosis, were used in this study. Two groups, each comprising of 10 rats, were formed. Group I served as a control group, and fibrin tissue adhesive was applied to group II.
Kockaya, EVRİM ARZU+3 more
openaire +3 more sources
Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets [PDF]
Although tissue factor (TF), the principial initiator of physiological coagulation and pathological thrombosis, has recently been proposed to be present in human blood, the functional significance and location of the intravascular TF is unknown.
Alex, Meike+9 more
core +1 more source
Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques [PDF]
Background: In most models of experimental thrombosis, healthy blood vessels are damaged. This results in the formation of a platelet thrombus that is stabilized by ADP signaling via P2Y(12) receptors.
J. J. J. van Giezen+9 more
core +3 more sources
The Use of Poly(vinyl alcohol)-based Hydrogels in Biomedical Applications [PDF]
Polymers have found increasing favor in biomedical applications due to the greater control that researchers can exert over their properties. Researchers have focused on the development of therapies using biologically compatible polymers due to their ...
Subramanian, Deepak
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Macromolecular approaches to prevent thrombosis and intimal hyperplasia following percutaneous coronary intervention. [PDF]
Cardiovascular disease remains one of the largest contributors to death worldwide. Improvements in cardiovascular technology leading to the current generation of drug-eluting stents, bioresorbable stents, and drug-eluting balloons, coupled with advances ...
Panitch, Alyssa, Scott, Rebecca A
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Anastomosis of the Intratemporal Facial Nerve Using Fibrin Tissue Adhesive [PDF]
This work aimed at studying the results obtained by the repair of complete lesions of the facial nerve in its intratemporal portions. Clinical, electrophysiological and surgical techniques were studied. Twenty-three patients with traumatic facial nerve lesions were operated. Nerve grafts were made in 10, and end-to-end anastomosis in thirteen.
Aroldo Miniti, Ricardo Ferreira Bento
openaire +2 more sources
Three-dimensional Migration of Neurites Is Mediated by Adhesion Site Density and Affinity [PDF]
Three-dimensional neurite outgrowth rates within fibrin matrices that contained variable amounts of RGD peptides were shown to depend on adhesion site density and affinity. Bi-domain peptides with a factor XIIIa substrate in one domain and a RGD sequence
Hubbell, Jeffrey A., Schense, Jason C.
core
Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast+66 more
core +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source