Results 71 to 80 of about 26,266 (245)
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li+6 more
wiley +1 more source
Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]
Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena+12 more
core
Suspended Tissue Open Microfluidic Patterning (STOMP)
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack+22 more
wiley +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
Fibrin versus polyethylene glycol sealant: an experimental study in rabbits [PDF]
Fibrin glue has been applied universally in general surgery as an adhesive, hemostatic, or embolizing agent. In reconstructive surgery, fibrin has been used mainly for nerve and microvascular repair or as a substitute for sutures in skin closure and skin
Beer, Gertrude+4 more
core
CCS‐RSF@PRP hydrogel is engineered to structurally and functionally mimic the blood clot by integrating PPR, CCS, and RSF nanofibers through in situ activation of PRP. In a rat periodontitis model, CCS‐RSF@PRP hydrogel effectively promotes periodontal tissue repair, attributing to neutralizing the multiple proinflammatory mediators, thus rebuilding a ...
Yini Huangfu+14 more
wiley +1 more source
Debridement of wounds with honey [PDF]
Honey has been used as a debriding agent since ancient times. Its debriding properties have been rediscovered in more recent times, with various case reports published in the latter decades of the 20th century describing its effectiveness in cleaning up ...
Molan, Peter C.
core +1 more source
Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster+2 more
wiley +1 more source
Nozzle Jamming Granularized Blood‐Derived Proteins for Bioprinting Cell‐Instructive Architectures
This work describes an innovative strategy to transform blood‐derived materials into highly printable granular materials that can be used as cell‐instructive bioinks by applying nozzle jamming instead of conventional centrifugal jamming. These modular inks allowed for increased microporosity in large 3D‐printed constructs, biocompatibility, and drug ...
Lucas S. Ribeiro+6 more
wiley +1 more source
A Current Overview of Materials and Strategies for Potential Use in Maxillofacial Tissue Regeneration [PDF]
Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The production of biodegradable, customizable scaffolds to achieve this clinical aim is dependent on the interdisciplinary collaboration among clinicians, bioengineers ...
Almeida, Luis Eduardo+7 more
core +1 more source