Results 91 to 100 of about 510,893 (315)
Fibroblasts in fibrosis: novel roles and mediators
Frontiers in Pharmacology, 2014 Fibroblasts are the most common cell type of the connective tissues found throughout the body and the principal source of the extensive extracellular matrix (ECM) characteristic of these tissues.
Ryan Thomas Kendall +1 more
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ACTION OF SHAKEN SERUM ON HOMOLOGOUS FIBROBLASTS [PDF]
, 1922 Alexis Carrel, Albert H. Ebeling
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FEBS Open Bio, EarlyView.We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang +9 more
wiley +1 more source
Mechanotransduction in fibroblasts
, 2011 Response to mechanical stress is important for tissue homeostasis, tissue architecture and muscle regeneration. All cells of an organism are subject to at least one of three types of mechanical stress: compression, shear stress or tension. The exact mechanisms how a cell senses mechanical stress and how it converts mechanical into chemical signals are ...
openaire +3 more sources
Frontiers in Pharmacology, 2018 This study aimed to explore the protective effects of a Chinese herbal formula, Jinshui Huanxian formula (JHF), on experimental pulmonary fibrosis and its underlying mechanisms. After being treated with single dose of bleomycin (5 mg/kg) intratracheally,
Yunping Bai +15 more
doaj +1 more source
THE FUNDAMENTAL PROPERTIES OF THE FIBROBLAST AND THE MACROPHAGE [PDF]
, 1926 Alexis Carrel, Albert H. Ebeling
openalex +1 more source
FEBS Open Bio, EarlyView.ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel +3 more
wiley +1 more source
THE EFFECT OF HYPOTONIC AND HYPERTONIC SOLUTIONS ON FIBROBLASTS OF THE EMBRYONIC CHICK HEART IN VITRO [PDF]
, 1919 Mary Jane Hogue
openalex +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
FEBS Open Bio, EarlyView.Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji +3 more
wiley +1 more source