Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies
Aging and Cancer, EarlyView.This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal +8 more
wiley +1 more source
EFFECT OF LIVER AND PITUITARY DIGESTS ON THE PROLIFERATION OF SARCOMATOUS FIBROBLASTS OF THE RAT [PDF]
, 1928 Lillian E. Baker, Alexis Carrel
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Identifying the mechanism for superdiffusivity in mouse fibroblast motility [PDF]
arXiv, 2017 We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displacements scale faster than t^(1/2) in all directions. Two mechanisms have been proposed to explain such statistics in other cell types: run and tumble behavior with L\'{e}vy ...
arxiv
A Method of Obtaining Tissue Cultures of Adult Fibroblasts [PDF]
, 1944 P. R. Peacock, R. I. SHUKOFF
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Fibroblast biology. Development and differentiation of synovial fibroblasts in arthritis.
Arthritis research, 2000 Synovial fibroblasts occur as two phenotypes--intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1 (VCAM-1) and complement decay-accelerating factor (DAF).
openaire +3 more sources
New Antifibroblastic Medication in Dermatology: Could Nintedanib Treat Scarring?
International Journal of General Medicine, 2022 Patricia Liana Cristodor,1,2,* Alexandru Nechifor,3,* Silvia Fotea,3,* Thomas Nadasdy,2,4 Yousef Bahloul,2,5 Alin Codrut Nicolescu,6,* Alin Laurentiu Tatu3,4,7,8 1Center for the Morphologic Study of the Skin MORPHODERM, University of ...
Cristodor PL +6 more
doaj
CENTRIOLES AND THE FORMATION OF RUDIMENTARY CILIA BY FIBROBLASTS AND SMOOTH MUSCLE CELLS [PDF]
, 1962 Sergei P. Sorokin
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EFFECTS OF 17-ß-ESTRADIOL AND OF GROWTH HORMONE ON THE PRODUCTION OF ACID MUCOPOLYSACCHARIDES BY HUMAN EMBRYONAL FIBROBLASTS IN VITRO [PDF]
, 1964 Luciano Ozzello
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Novel Phenotypes and Deep Intronic Variant Expand TH‐Associated Dopa‐Responsive Dystonia Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Approximately 20% of dopa‐responsive dystonia (DRD) cases remain genetically unresolved. Using whole‐genome sequencing, we identified two TH variants in a young DRD patient, including a novel deep intronic variant. Minigene assays confirmed that this variant causes aberrant splicing.
Xiaosheng Zheng +6 more
wiley +1 more source