Results 251 to 260 of about 1,131,844 (424)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Fibroblast atlas: Shared and specific cell types across tissues. [PDF]

Sci Adv
Liu K, Cui Y, Han H, Guo E, Shi X, Xiong K, Zhang N, Zhai S, Sang S, Liu M, Chen B, Gu Y.   +11 more
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Investigation of the role of GEM in systemic lupus erythematosus through multi-omics joint analysis. [PDF]

Front Immunol
Chen R, Zhang X, Shang Y, Zhang H, Li X, Dai H, Shuai Z.   +6 more
europepmc   +1 more source

The incorporation of thymidine into deoxyribonucleic acid in mouse fibroblasts infected with polyoma virus [PDF]

, 1966
P. Molteni, Vincenzo De Simone, E Grosso, PA Bianchi, E. Polli   +4 more
openalex   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Single-Cell Transcriptomics Revealed E-Cigarettes-Induced Vascular Remodeling by Enhancing <i>Tcf21</i> Expression. [PDF]

MedComm (2020)
Ding R, Ren X, Sun Q, Liu S, Huang L, Sun Z, Duan J.   +6 more
europepmc   +1 more source

Influence of Steroids on Fibroblasts. I. An In Vitro Fibroblast Assay for Corticosteroids**Department of Anatomy, University of Utah Medical Center, Salt Lake City.

, 1967
David L. Berliner, Ann G. Ruhmann
openalex   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

Advanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi, Marina BenShoshan, Adi Liiani, Tomer Reuveni, Offir Loboda, Moti Harats, Josef Haik, Itzhak Binderman, Yosi Shacham‐Diamand, Amit Sitt, Ayelet Di Segni, Lihi Adler‐Abramovich   +11 more
wiley   +1 more source