A novel cancer-associated fibroblast-related gene signature for predicting diffuse large B cell lymphoma prognosis using weighted gene co-expression network analysis and machine learning. [PDF]
J Int Med ResCui H, Chen M, Zhao M, Li B.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li +9 more
wiley +1 more source
Fibroblast heterogeneity: implications for human disease
Journal of Clinical Investigation, 2018 M. Lynch, F. Watt
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon +6 more
wiley +1 more source
Crosstalk between T cells and fibroblasts in biomaterial-mediated fibrosis. [PDF]
Matrix Biol PlusKibet M, Abebayehu D.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang +14 more
wiley +1 more source
Modulation of the tumor microenvironment by zerumbone and 5-fluorouracil in colorectal cancer by target in cancer-associated fibroblasts. [PDF]
Discov OncolNobari S +4 more
europepmc +1 more source
alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. [PDF]
, 1979 Mark C. Willingham +2 more
openalex +1 more source
Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction
Advanced Healthcare Materials, EarlyView.This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi +13 more
wiley +1 more source
Development and characterization of a novel immortalized human vaginal fibroblast cell line for advanced applications in reproductive health. [PDF]
Reprod Biol EndocrinolCheng LC, You S, Ren T, Qiu J, Hua K.
europepmc +1 more source