Results 281 to 290 of about 510,893 (315)
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Reduced response of scleroderma fibroblasts to fibroblast growth factor
Archives of Dermatological Research, 1984Reactivity of scleroderma fibroblasts to lymphoid cell-derived fibroblast growth factor (FGF) was assessed in this study. The fibroblasts from the sclerotic lesion failed to respond to FGF, whereas those from scleroedematous lesions responded equally to normal fibroblast.
Shigeharu Sano +3 more
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2002
Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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Publisher Summary Fibroblasts are the most abundant cells in the lungs. They are primarily responsible for producing the extracellular matrix proteins that maintain the structure of the airways and lung parenchyma. Myofibroblasts are found in the lamina reticularis and appear as multicellular strands.
Robin J. McAnulty, Geoffrey J. Laurent
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2009
Publisher Summary This chapter explores the current knowledge about the role of fibroblasts in lung homeostasis and pathological disorders associated with chronic remodeling. It also reviews the potential of opportunities arising for better therapeutic intervention strategies targeting fibroblasts that will either halt or potentially reverse fibrosis.
Lynne A. Murray +2 more
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Publisher Summary This chapter explores the current knowledge about the role of fibroblasts in lung homeostasis and pathological disorders associated with chronic remodeling. It also reviews the potential of opportunities arising for better therapeutic intervention strategies targeting fibroblasts that will either halt or potentially reverse fibrosis.
Lynne A. Murray +2 more
openaire +2 more sources
Clinical and Experimental Nephrology, 1998
During recent years, fibroblasts have been recognized as a heterogenous cell type with a remarkable degree of differentiation and important functional properties in health and in disease. Our better understanding of the biology of fibroblasts has elucidated some of the mechanisms responsible for fibrosis of the kidney and other organs.
Volker Becker, Gerhard A. Müller
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During recent years, fibroblasts have been recognized as a heterogenous cell type with a remarkable degree of differentiation and important functional properties in health and in disease. Our better understanding of the biology of fibroblasts has elucidated some of the mechanisms responsible for fibrosis of the kidney and other organs.
Volker Becker, Gerhard A. Müller
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2007
Extensive research has shown that connective tissues such as tendons and ligaments are able to respond to mechanical forces by changing their structure, composition, and function. This mechanical adaptation is made possible largely by fibroblasts, the major cell types responsible for maintaining, repairing, and remodeling extracellular matrix (ECM) in ...
Bhavani P. Thampatty, James H.-C. Wang
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Extensive research has shown that connective tissues such as tendons and ligaments are able to respond to mechanical forces by changing their structure, composition, and function. This mechanical adaptation is made possible largely by fibroblasts, the major cell types responsible for maintaining, repairing, and remodeling extracellular matrix (ECM) in ...
Bhavani P. Thampatty, James H.-C. Wang
openaire +2 more sources
American Journal of Respiratory and Critical Care Medicine, 2006
Anna Luise A Katzenstein +1 more
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Anna Luise A Katzenstein +1 more
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Fibroblasts and Fibroblast-like Synoviocytes
2013A Filer, Christopher D. Buckley
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