Results 121 to 130 of about 11,581,273 (293)

Randomized Clinical Trial of Sevelamer Carbonate on Serum Klotho and Fibroblast Growth Factor 23 in CKD

, 2017
International audienceBackground and objectives: Epidemiologic studies suggest that higher serum phosphaturic hormone fibroblast growth factor 23 levels are associated with increase morbidity and mortality.
Sophie Liabeuf, Denis Fouque, Liabeuf, Sophie, Gabriel Choukroun, Mentaverri, Romuald, Christian Combe, Vanhille, Philippe, Luc Frimat, Ryckelynck, Jean-Philippe, Thervet, Eric, Combe, Christian, Dussol, Bertrand, Frimat, Luc, Jean-Philippe Ryckelynck, Choukroun, Gabriel, Pablo Ureña, Prie, Dominique, Najeh El Esper, Dominique Prié, Romuald Mentaverri, Urena, Pablo, Fouque, Denis, Bertrand Dussol, El Esper, Najeh, null null, Eric Thervet, Philippe Vanhille   +26 more
core   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Charting Morphotoxicity With Complementary Embryo Models

Advanced Healthcare Materials, EarlyView.
Three human embryo models of the peri‐implantation stages are exposed to a library of compounds. The (toxic) effects of the compounds are analyzed through automated image analysis pipelines. By evaluating the differential responses of the embryo models, this study underscores the importance of testing complementary embryo models to achieve robust and ...
Dorian G. Luijkx, Pauline L. Balder, Romy M. L. Verhagen, Vinidhra Shankar, Barry Jutten, Pinak Samal, Timo Rademakers, Clemens A. van Blitterswijk, Stefan Giselbrecht, Erik J. Vrij   +9 more
wiley   +1 more source

Physiological concentrations of gangliosides GM1, GM2 and GM3 differentially modify basic-fibroblast-growth-factor-induced mitogenesis and the associated signalling pathway in endothelial cells

, 1999
It has been suggested that gangliosides can influence the growth of cells by modulation of growth-factor-receptor signalling. The activation of endothelial cells (EC) during angiogenesis is crucial for tumour growth and for metastasis, also for numerous ...
Shant Kumar (83955), Mark Slevin (41459), Xiaotong He (303933), John Gaffney (41466)   +3 more
core  

Fibroblast growth factor-23 concentrations in polycystic ovary syndrome

, 2018
Objective: This study was designed to compare the serum concentrations of Fibroblast growth factor 23 (FGF23) among patients with PCOS and healthy subjects and to evaluate the relation between the hormonal and metabolic ...
Kizilgul, Muhammed, Caliskan, Mustafa, Apaydin, Mahmut, Demirci, Taner, Arslan, Muyesser Sayki, Cakal, Erman, Culha, Cavit, ÇELİK, BÜLENT, Kan, Seyfullah   +8 more
core   +1 more source

Fibroblast growth factor 23 [PDF]

, 2020
openaire   +2 more sources

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

Enhanced effect of fibroblast growth factor-2-containing dalteparin/protamine nanoparticles on hair growth

, 2016
Yuki Takabayashi,1 Masaki Nambu,1 Masayuki Ishihara,2 Masahiro Kuwabara,1 Koichi Fukuda,2 Shingo Nakamura,2 Hidemi Hattori,2Tomoharu Kiyosawa1 1Department of Plastic and Reconstructive Surgery, 2Division of Biomedical ...
Nambu M, Fukuda K, Hattori H, Kiyosawa T, Kuwabara M, Takabayashi Y, Ishihara M, Nakamura S   +7 more
core  

The Interplay Between Bone Biology and Iron Metabolism: Molecular Mechanisms and Clinical Implications

Biomedicines
The maintenance of bone homeostasis requires the coordinated activity of specialized cells (osteoblasts, osteoclasts and osteocytes), soluble factors and hormones with regulatory functions.
Margherita Correnti, Elena Gammella, Gaetano Cairo, Stefania Recalcati   +3 more
doaj   +1 more source

A Systematic Study of GelMA‐Carbopol Bioinks for High‐Fidelity Extrusion 3D Bioprinting at Physiological Temperatures

Advanced Healthcare Materials, EarlyView.
Gonzalez Martinez and collaborators develop a strategy to formulate high performance GelMA‐based bioinks with low solids contents. The resulting bioinks enable 3D bioprinting at 37 °C of high‐fidelity structures with tunable mechanical properties that support high cell viability and function.
David A. González‐Martínez, Aidee V. Arizpe Tafoya, Eduardo González‐Martínez, Mabel Barreiro Carpio, Laura Daniela Serrano Andrade, Christopher T. N. Chow, Mohammadhossein Dabaghi, Jeremy A. Hirota, Jose M. Moran‐Mirabal   +8 more
wiley   +1 more source