Results 1 to 10 of about 2,273 (114)

Fibroblast Growth Factors in Depression [PDF]

open access: yesFrontiers in Pharmacology, 2019
Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood.
Zheng Deng   +7 more
doaj   +3 more sources

Role of FGF-18 in Bone Regeneration

open access: yesJournal of Functional Biomaterials, 2023
In tissue engineering, three key components are cells, biological/mechanical cues, and scaffolds. Biological cues are normally proteins such as growth factors and their derivatives, bioactive molecules, and the regulators of a gene.
Kavipriya Murugaiyan   +3 more
doaj   +1 more source

Conversion of a Paracrine Fibroblast Growth Factor into an Endocrine Fibroblast Growth Factor [PDF]

open access: yesJournal of Biological Chemistry, 2012
FGFs 19, 21, and 23 are hormones that regulate in a Klotho co-receptor-dependent fashion major metabolic processes such as glucose and lipid metabolism (FGF21) and phosphate and vitamin D homeostasis (FGF23). The role of heparan sulfate glycosaminoglycan in the formation of the cell surface signaling complex of endocrine FGFs has remained unclear. Here
Goetz R   +10 more
openaire   +2 more sources

The Regenerative Potential of bFGF in Dental Pulp Repair and Regeneration

open access: yesFrontiers in Pharmacology, 2021
Regenerative endodontic therapy intends to induce the host’s natural wound-healing process, which can restore the vitality, immunity, and sensitivity of the inflammatory or necrotic pulp tissue destroyed by infection or trauma.
Keyue Liu, Sijing Yu, Ling Ye, Bo Gao
doaj   +1 more source

Comparative genomic analysis of eutherian fibroblast growth factor genes

open access: yesBMC Genomics, 2020
Background The eutherian fibroblast growth factors were implicated as key regulators in developmental processes. However, there were major disagreements in descriptions of comprehensive eutherian fibroblast growth factors gene data sets including either ...
Marko Premzl
doaj   +1 more source

Serum intact fibroblast growth factor 23 in healthy paediatric population

open access: yesOpen Medicine, 2021
It is believed that fibroblast growth factor 23 (FGF23) can become an early biomarker of chronic kidney disease progression. Data on FGF23 age dependency are inconsistent.
Stanczyk Malgorzata   +3 more
doaj   +1 more source

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis [PDF]

open access: yesCytokine & Growth Factor Reviews, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans, and integrins.
PRESTA, Marco   +5 more
openaire   +3 more sources

The Efficacy of Fibroblast Growth Factor for the Treatment of Chronic Vocal Fold Scarring: From Animal Model to Clinical Application [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2017
Objectives This study assessed the regenerative efficacy of basic fibroblast growth factor (FGF) in a rabbit model of chronic vocal fold scarring and then confirmed its utility and safety in a prospective trial of patients with this condition.
Myung Jin Ban   +6 more
doaj   +1 more source

Endocrine Fibroblast Growth Factors in Relation to Stress Signaling

open access: yesCells, 2022
Fibroblast growth factors (FGFs) play important roles in various growth signaling processes, including proliferation, development, and differentiation.
Makoto Shimizu, Ryuichiro Sato
doaj   +1 more source

Fibroblast growth factors as tissue repair and regeneration therapeutics [PDF]

open access: yesPeerJ, 2016
Cell communication is central to the integration of cell function required for the development and homeostasis of multicellular animals. Proteins are an important currency of cell communication, acting locally (auto-, juxta-, or paracrine) or ...
Quentin M. Nunes   +4 more
doaj   +2 more sources

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