Results 31 to 40 of about 450,978 (295)

Novel targeted agents for the treatment of bladder cancer: translating laboratory advances into clinical application

open access: yesInternational Brazilian Journal of Urology, 2010
Bladder cancer is a common and frequently lethal cancer. Natural history studies indicate two distinct clinical and molecular entities corresponding to invasive and non-muscle invasive disease.
Xiaoping Yang, Thomas W. Flaig
doaj   +1 more source

Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair [PDF]

open access: yes, 2000
We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a ...
Dallon, J. C.   +3 more
core   +1 more source

Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice

open access: yesFrontiers in Pharmacology, 2021
FGF5 and FGF18 are key factors in the regulation of the hair follicle cycle. FGF5 is overexpressed during the late anagen phase and serves as a crucial regulatory factor that promotes the anagen-to-catagen transition in the hair follicle cycle.
Jungang Zhao   +9 more
doaj   +1 more source

Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers. [PDF]

open access: yes, 2016
PurposeWe present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2.
Akil, Handan   +5 more
core   +3 more sources

Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]

open access: yes, 1993
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael   +2 more
core   +1 more source

The effect of endurance resistance exercise combined with L­citrulline malate supplement on FGF, VEGF, and fatigue among young bodybuilders [PDF]

open access: yesفصلنامه ابن سینا, 2019
Background: Citrulline malate is a non-essential alpha-amino acid supplement resulting from arginine oxidation and may cause changes in the immunity, cardiovascular, and angiogenic mechanisms. It also reduces the rating of fatigue perception. The purpose
farah nameni   +1 more
doaj  

Semen Modulates Cell Proliferation and Differentiation-Related Transcripts in the Pig Peri-Ovulatory Endometrium

open access: yesBiology, 2022
Uterine homeostasis is maintained after mating by eliminating pathogens, foreign cells, and proteins by a transient inflammation of the uterus. Such inflammation does not occur in the oviductal sperm reservoir (utero-tubal junction, UTJ), colonized by a ...
Jaume Gardela   +6 more
doaj   +1 more source

Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]

open access: yes, 2017
The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert   +3 more
core   +2 more sources

Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation

open access: yesiScience, 2019
Summary: Lung epithelial cells and fibroblasts are key cell populations in lung development. Fibroblasts support type 2 alveolar epithelial cells (AEC2) in the developing and mature lung.
Kazushige Shiraishi   +6 more
doaj   +1 more source

A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor. [PDF]

open access: yes, 2013
Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular functions, from wound healing to bone regeneration.
Decker, Caitlin G   +5 more
core   +1 more source

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