Bladder cancer is a common and frequently lethal cancer. Natural history studies indicate two distinct clinical and molecular entities corresponding to invasive and non-muscle invasive disease.
Xiaoping Yang, Thomas W. Flaig
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Biological implications of a discrete mathematical model for collagen deposition and alignment in dermal wound repair [PDF]
We deveiop a novel mathematical model for collagen deposition and alignment during dermal wound healing. We focus on the interactions between fibroblasts, modelled as discrete entities, and a continuous extracellular matrix composed of collagen and a ...
Dallon, J. C. +3 more
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Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice
FGF5 and FGF18 are key factors in the regulation of the hair follicle cycle. FGF5 is overexpressed during the late anagen phase and serves as a crucial regulatory factor that promotes the anagen-to-catagen transition in the hair follicle cycle.
Jungang Zhao +9 more
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Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers. [PDF]
PurposeWe present a case of bilateral extensive peripapillary myelinated retinal nerve fibers (MRNF) in an individual with Crouzon syndrome, an inherited form of craniosynostosis caused by overactivation of fibroblast growth factor receptor 2.
Akil, Handan +5 more
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Extinction of gene expression in somatic cell hybrids. a reflection of important regulatory mechanisms? [PDF]
Extinction in somatic cell hybrids is a multifactorial process that leads to loss of cell-type-specific gene expression. The underlying mechanisms are thought to mirror, at least in part, the repertoire of regulatory mechanisms controlling mammalian cell
Boshart, Michael +2 more
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The effect of endurance resistance exercise combined with Lcitrulline malate supplement on FGF, VEGF, and fatigue among young bodybuilders [PDF]
Background: Citrulline malate is a non-essential alpha-amino acid supplement resulting from arginine oxidation and may cause changes in the immunity, cardiovascular, and angiogenic mechanisms. It also reduces the rating of fatigue perception. The purpose
farah nameni +1 more
doaj
Uterine homeostasis is maintained after mating by eliminating pathogens, foreign cells, and proteins by a transient inflammation of the uterus. Such inflammation does not occur in the oviductal sperm reservoir (utero-tubal junction, UTJ), colonized by a ...
Jaume Gardela +6 more
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Hepatocyte growth factor, a key tumor-promoting factor in the tumor microenvironment [PDF]
The tumor microenvironment plays a key role in tumor development and progression. Stromal cells secrete growth factors, cytokines and extracellular matrix proteins which promote growth, survival and metastatic spread of cancer cells.
Galemmo, Robert +3 more
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Summary: Lung epithelial cells and fibroblasts are key cell populations in lung development. Fibroblasts support type 2 alveolar epithelial cells (AEC2) in the developing and mature lung.
Kazushige Shiraishi +6 more
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A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor. [PDF]
Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular functions, from wound healing to bone regeneration.
Decker, Caitlin G +5 more
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