Results 41 to 50 of about 450,978 (295)

Gli1 mediates lung cancer cell proliferation and sonic hedgehog-dependent mesenchymal cell activation. [PDF]

open access: yes, 2013
Non-Small-Cell-Lung-Cancer (NSCLC) represents approximately 85% of all lung cancers and remains poorly understood. While signaling pathways operative during organ development, including Sonic Hedgehog (Shh) and associated Gli transcription factors (Gli1 ...
Bermudez, Olga   +4 more
core   +6 more sources

Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice

open access: yesFrontiers in Cell and Developmental Biology, 2021
Placodes are ectodermal thickenings of the embryonic vertebrate head. Their descendants contribute to sensory organ development, but also give rise to sensory neurons of the cranial nerves.
Stefan Washausen, Wolfgang Knabe
doaj   +1 more source

Evaluating the Fibroblast Growth Factor-23 and Phosphate in Iraqi Patients with Acromegaly

open access: yesمجلة بغداد للعلوم
Fibroblast growth factors-23 (FGF-23) are a class of cell signaling proteins produced by macrophages. They have a range of roles, but they play a particularly important role in the development of animal cells, where they are essential for appropriate ...
Sara A. Kashash, Areej Sh. Hameed
doaj   +1 more source

Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements

open access: yesFrontiers in Cellular Neuroscience, 2013
The transformation of a normal brain in epileptic (epileptogenesis) is associated with extensive morpho-functional alterations, including cell death, axonal and dendritic plasticity, neurogenesis, and others. Neurotrophic factors (NTFs) appear to be very
Beatrice eParadiso   +2 more
doaj   +1 more source

System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. [PDF]

open access: yesPLoS Genetics, 2013
Many fibroblast-secreted proteins promote tumorigenicity, and several factors secreted by cancer cells have in turn been proposed to induce these proteins.
Megha Rajaram   +3 more
doaj   +1 more source

Fibroblast growth factor 2

open access: yesDifferentiation
Fibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation.
Audrey Nickle   +2 more
openaire   +3 more sources

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]

open access: yes, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core   +1 more source

Model of the early development of thalamo-cortical connections and area patterning via signaling molecules

open access: yes, 2004
The mammalian cortex is divided into architectonic and functionally distinct areas. There is growing experimental evidence that their emergence and development is controlled by both epigenetic and genetic factors.
Ermentrout, G. B., Karbowski, Jan
core   +3 more sources

Oxidized (non)-regenerated cellulose affects fundamental cellular processes of wound healing. [PDF]

open access: yes, 2016
In this study we investigated how hemostats such as oxidized regenerated cellulose (ORC, TABOTAMP) and oxidized non-regenerated cellulose (ONRC, RESORBA CELL) influence local cellular behavior and contraction of the extracellular matrix (ECM).
Ibing, W   +6 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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