Results 41 to 50 of about 1,940,282 (341)

Mesenchymal-Epithelial Interactome Analysis Reveals Essential Factors Required for Fibroblast-Free Alveolosphere Formation

iScience, 2019
Summary: Lung epithelial cells and fibroblasts are key cell populations in lung development. Fibroblasts support type 2 alveolar epithelial cells (AEC2) in the developing and mature lung.
Kazushige Shiraishi, Shigeyuki Shichino, Satoshi Ueha, Takuya Nakajima, Shinichi Hashimoto, Satoshi Yamazaki, Kouji Matsushima   +6 more
doaj   +1 more source

Responses of Epibranchial Placodes to Disruptions of the FGF and BMP Signaling Pathways in Embryonic Mice

Frontiers in Cell and Developmental Biology, 2021
Placodes are ectodermal thickenings of the embryonic vertebrate head. Their descendants contribute to sensory organ development, but also give rise to sensory neurons of the cranial nerves.
Stefan Washausen, Wolfgang Knabe
doaj   +1 more source

Metabolic fibroblast growth factors (FGFs): Mediators of energy homeostasis

Seminars in Cell and Developmental Biology, 2015
The metabolic fibroblast growth factors (FGFs), FGF1, FGF15/19, and FGF21 differ from classic FGFs in that they modulate energy homeostasis in response to fluctuating nutrient availability.
Kathleen R. Markan, Matthew J. Potthoff
semanticscholar   +1 more source

Evaluating the Fibroblast Growth Factor-23 and Phosphate in Iraqi Patients with Acromegaly

مجلة بغداد للعلوم
Fibroblast growth factors-23 (FGF-23) are a class of cell signaling proteins produced by macrophages. They have a range of roles, but they play a particularly important role in the development of animal cells, where they are essential for appropriate ...
Sara A. Kashash, Areej Sh. Hameed
doaj   +1 more source

A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation

, 2009
Background: The fibroblast growth factors (FGFs) are key regulators of embryonic development, tissue homeostasis and tumour angiogenesis. Binding of FGFs to their receptor(s) results in activation of several intracellular signalling cascades including ...
Maffucci, Tania, Dominguez, V., Tania Maffucci, Gianluca Sala, Raimondi C, Dominguez V, Dominguez Veronica, Abu-Hayyeh S, Zachary I, Falasca Marco, Raimondi Claudio, Sala, Gianluca, Claudio Raimondi, Maffucci Tania, Abu-Hayyeh, Shadi, Falasca, Marco, Zachary, Ian, Raimondi, C, Sala, G, Abu-Hayyeh, S, Veronica Dominguez, Zachary, I., Falasca M, Maffucci T, Maffucci, T, Ian Zachary, Dominguez, Veronica, Sala G, Falasca, M, Sala Gianluca, Shadi Abu-Hayyeh, Marco Falasca, Maffucci, T., Sala, G., Abu-Hayyeh Shadi, Raimondi, C., Dominguez, V, Zachary, I, Raimondi, Claudio, Zachary Ian, Abu-Hayyeh, S.   +40 more
core   +1 more source

Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements

Frontiers in Cellular Neuroscience, 2013
The transformation of a normal brain in epileptic (epileptogenesis) is associated with extensive morpho-functional alterations, including cell death, axonal and dendritic plasticity, neurogenesis, and others. Neurotrophic factors (NTFs) appear to be very
Beatrice eParadiso, Silvia eZucchini, Michele eSimonato   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Functional Diversity of Fibroblast Growth Factors in Bone Formation

International Journal of Endocrinology, 2015
The functional significance of fibroblast growth factor (FGF) signaling in bone formation has been demonstrated through genetic loss-of-function and gain-of-function approaches.
Yuichiro Takei, Tomoko Minamizaki, Yuji Yoshiko   +2 more
doaj   +1 more source

Fibroblast growth factor 2

Differentiation
Fibroblast Growth Factor 2 (FGF2), also known as basic fibroblast growth factor, is a potent stimulator of growth and differentiation in multiple tissues. Its discovery traces back over 50 years ago when it was first isolated from bovine pituitary extracts due to its ability to stimulate fibroblast proliferation.
Audrey Nickle, Sebastian Ko, Amy E. Merrill   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source