Results 61 to 70 of about 1,940,282 (341)
Fibroblast Growth Factor Inhibitors [PDF]
Journal of Thoracic Oncology, 2010 Dr. Ignatio Witsuba (MD Anderson) started this session by giving an overview of the fibroblast growth factor (FGF) pathway and expression of FGFs (22 members), FGF receptors (FGFRs, four members), and their gene family members in non-small cell lung cancer (NSCLC).
openaire +2 more sources
Growth factor regulation of growth factor production by multiple gene transfer to chondrocytes
, 2013 Of the many classes of molecules regulated by growth factors, growth factors themselves are not well investigated. We tested the hypothesis that combinations of endogenous growth factors interactively regulate the production of other growth factors ...
Trippel, Stephen B. +3 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Journal of Neuroinflammation, 2019 Background Herpes simplex virus-1 (HSV-1) infections of the central nervous system (CNS) can result in HSV-1 encephalitis (HSE) which is characterized by severe brain damage and long-term disabilities.
Niko Hensel +17 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FGFRL1 is a neglected putative actor of the FGF signalling pathway present in all major metazoan phyla [PDF]
, 2009 Association pour la Recherche contre le Cancer, Centre National de la Recherche Scientifique, the European Molecular Biology Organization, and the Cascade network of excellence in the 6th Framework Programme for financial support. The laboratory of HE is
Garcia-Fernandez Jordi +9 more
core +1 more source
Journal of Experimental Medicine, 1986 Tumor necrosis factor (TNF) is a monocyte-derived protein cytotoxic or cytostatic for some tumor cell lines. Here we show that highly purified E. coli-derived recombinant human TNF stimulated the growth of human FS- 4 diploid fibroblasts.
J. Vilček +6 more
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
F1000ResearchFibroblasts are cells of mesenchymal origin that are found throughout the body. While these cells have several functions, their integral roles include maintaining tissue architecture through the production of key extracellular matrix components, and ...
Matthew B. Buechler +2 more
doaj +1 more source
Effect of cupuassu butter on human skin cells
Data in Brief, 2018 This study investigated the effect of cupuassu butter on the cell number of human skin fibroblasts, as well as the gene expression profiles of certain growth factors in these fibroblasts.
Katsura Sano +2 more
doaj +1 more source