Role of fibroblast growth factors in bone regeneration [PDF]
Inflammation and Regeneration, 2017 Bone is a metabolically active organ that undergoes continuous remodeling throughout life. However, many complex skeletal defects such as large traumatic bone defects or extensive bone loss after tumor resection may cause failure of bone healing ...
Pornkawee Charoenlarp +2 more
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Fibroblast growth factors [PDF]
Current Biology, 2003 What are they? Fibroblast growth factors (FGFs) are a family of small (20–30kDa) intercellular signalling proteins which are frequently found to be glycosylated. The first draft of the human genome identified 29 potential FGF genes, and so far transcripts have been identified for 23 of them.
I. Mason
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Fibroblast growth factors induce hepatic tumorigenesis post radiofrequency ablation [PDF]
Scientific Reports, 2023 Image-guided radiofrequency ablation (RFA) is used to treat focal tumors in the liver and other organs. Despite potential advantages over surgery, hepatic RFA can promote local and distant tumor growth by activating pro-tumorigenic growth factor and ...
Aurelia Markezana +14 more
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Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration [PDF]
Journal of Tissue Engineering, 2010 Fibroblast growth factors (FGFs) that signal through FGF receptors (FGFRs) regulate a broad spectrum of biological functions, including cellular proliferation, survival, migration, and differentiation.
Ye-Rang Yun +8 more
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Recent Advances in the Role of Fibroblast Growth Factors in Hair Follicle Growth [PDF]
BiomoleculesHair follicles are essential to hair formation and cyclic regeneration, experiencing growth and degeneration, and quiescence phases involving complex signaling pathways.
Junchao Wang +3 more
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Stem Cell Reports, 2015 Fibroblasts can be directly reprogrammed into cardiomyocyte-like cells (iCMs) by overexpression of cardiac transcription factors, including Gata4, Mef2c, and Tbx5; however, this process is inefficient under serum-based culture conditions, in which ...
Hiroyuki Yamakawa +13 more
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Roles of Fibroblast Growth Factors and Their Therapeutic Potential in Treatment of Ischemic Stroke [PDF]
Frontiers in Pharmacology, 2021 Stroke is the leading cause of death worldwide, and its treatment remains a challenge. Complex pathological processes are involved in stroke, which causes a reduction in the supply of oxygen and energy to the brain that triggers subsequent cascade events,
Confidence Dordoe +8 more
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Antagonism of interferon signaling by fibroblast growth factors promotes viral replication [PDF]
EMBO Molecular Medicine, 2020 Fibroblast growth factors (FGFs) play key roles in the pathogenesis of different human diseases, but the cross‐talk between FGFs and other cytokines remains largely unexplored.
Luigi Maddaluno +17 more
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Fibroblast Growth Factors in the Management of Acute Kidney Injury Following Ischemia-Reperfusion [PDF]
Frontiers in Pharmacology, 2020 Ischemia-reperfusion injury (IRI), which is triggered by a transient reduction or cessation of blood flow followed by reperfusion, is a significant cause of acute kidney injury (AKI).
Lian-Cheng Deng +5 more
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Sulfated polysaccharides interact with fibroblast growth factors and protect from denaturation [PDF]
FEBS Open Bio, 2019 Fibroblast growth factors (FGFs) regulate embryonic development and homeostasis, including tissue and organ repair and specific aspects of metabolism.
Changye Sun +6 more
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