Results 181 to 190 of about 243,457 (217)

Excess fibroblast growth factor 23 in alcoholic osteomalacia is derived from the bone. [PDF]

JBMR Plus
Hidaka N, Oyama Y, Koga M, Kondo N, Yasunaga Y, Shimakura T, Yamamoto N, Takahashi HE, Iwafuchi Y, Watanabe S, Kimura S, Hoshino Y, Kato H, Kinoshita Y, Kobayashi H, Tanaka T, Ushiku T, Nangaku M, Tanaka S, Makita N, Saito T, Ito N.   +21 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Fibroblast growth factor 23 predicts incident diabetic kidney disease: A 4.6-year prospective study. [PDF]

Diabetes Obes Metab
Liu D, Yu S, Zhang Y, Li Q, Kang P, Wang L, Han R, Cheng D, Chen A, Hou X, Wu L, Zang S, Fang Q, Jia W, Li H.   +14 more
europepmc   +1 more source

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

Weekly biological variation of serum biochemistry analytes and fibroblast growth factor 23 in healthy cats and cats with chronic kidney disease. [PDF]

J Small Anim Pract
Summers S, Szlosek D, Michael HT, Mack R.   +3 more
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Treatment-Resistant Hypophosphataemia After Ferric Carboxymaltose: Expanding the Spectrum of 6h Syndrome (Hypophosphataemia, Hyperphosphaturia, Hypovitaminosis D, Hypocalcaemia, Secondary Hyperparathyroidism, High Fibroblast Growth Factor-23). [PDF]

Eur J Case Rep Intern Med
Rashid L.
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Association of Fibroblast Growth Factor 23 and Cardiac Mechanics in the Cardiovascular Health Study. [PDF]

Kidney360
Jain K, Katz R, Isakova T, Kizer JR, Sharma S, Psaty BM, Shah SJ, Ix J, Mehta R.   +8 more
europepmc   +1 more source

Suppression of Fibroblast Growth Factor 23 in UMR106 Osteoblast-Like Cells and MC3T3-E1 Cells by Adipokine Chemerin. [PDF]

Cell Biochem Funct
Vogt J, Daferner K, Föller M.
europepmc   +1 more source