Results 71 to 80 of about 536,398 (346)
Association of Fibroblast Growth Factor 23 and Calcium in Chronic Kidney Disease Patients
Journal of Techniques, 2022 Chronic kidney disease (CKD) is a growing international health concern with elevating mortality rate in the world today and it is generally a progressive and irreversible issue.
Ghaith Hamza Kamil +2 more
doaj +1 more source
Journal of Bone and Mineral Research, 2020 Autosomal dominant hypophosphatemic rickets (ADHR) is caused by mutations impairing cleavage of fibroblast growth factor 23 (FGF23). FGF23 gene expression increases during iron deficiency.
E. Imel +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Tzu Chi Medical Journal, 2021 Objective: Homeostasis of serum phosphorus and calcitriol level is regulated mainly by fibroblast growth factor 23 (FGF23). Studies show that elevated serum FGF23 level was significantly associated with aortic calcification severity, peripheral blood ...
Riri Andri Muzasti, Netty Delvrita Lubis
doaj +1 more source
Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications. [PDF]
, 2015 Fibroblast growth factors (FGFs) and their receptors (FGFRs) are transmembrane growth factor receptors with wide tissue distribution. FGF/FGFR signaling is involved in neoplastic behavior and also development, differentiation, growth, and survival.
Helsten, Teresa +2 more
core +2 more sources
Journal of the American Society of Nephrology, 2019 BACKGROUND Higher serum phosphate and fibroblast growth factor-23 (FGF23) levels may be modifiable to prevent cardiovascular disease in CKD. Short-term studies have reported modest efficacy in phosphate and FGF23 reduction with intestinal phosphate ...
J. Ix +12 more
semanticscholar +1 more source
European Journal of Clinical Nutrition, 2020 The phosphaturic hormone fibroblast growth factor 23 (FGF23) is a risk marker of cardiovascular and all-cause mortality. We therefore aimed to synthesize the evidence for the effect of vitamin D administration on circulating FGF23 concentrations.
A. Zittermann, H. Berthold, S. Pilz
semanticscholar +1 more source
Cardiac actions of fibroblast growth factor 23 [PDF]
Bone, 2017 Fibroblast growth factors (FGF) are mitogenic signal mediators that induce cell proliferation and survival. Although cardiac myocytes are post-mitotic, they have been shown to be able to respond to local and circulating FGFs. While precise molecular mechanisms are not well characterized, some FGF family members have been shown to induce cardiac ...
openaire +2 more sources
Fibroblast Growth Factor-23 and Outcomes [PDF]
Journal of the American Society of Nephrology, 2013 Even after taking into account comorbidities, such as a diabetes and hypertension, that often accompany CKD, patients are plagued by a high risk of early mortality, particularly because of cardiovascular disease (CVD).[1][1] Focus on traditional risk factors from the general population, such ...
Ishir, Bhan, Ravi, Thadhani
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source