Results 221 to 230 of about 988,166 (377)
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Inhibition of adenosine/A2A receptor signaling suppresses dermal fibrosis by enhancing fatty acid oxidation. [PDF]
Zhang X+9 more
europepmc +1 more source
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li+9 more
wiley +1 more source
Nuclear CD24 promotes IL-6 secretion in fibroblasts. [PDF]
Sheng Y+7 more
europepmc +1 more source
This study reports a novel strategy for preparing a biocompatible adhesive hydrogel crosslinked with a muscle tissue‐derived extracellular matrix (MEM) for in situ muscle regeneration. As a natural crosslinker, MEM not only mediates combinatorial polymer networks but also stimulates satellite cells to induce a cell‐free therapeutic solution.
Eun Je Jeon+6 more
wiley +1 more source
Fibroblasts fluctuating between mesenchyme and epithelium are involved in hair follicle mesenchyme development. [PDF]
Hirose Y+9 more
europepmc +1 more source
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang+14 more
wiley +1 more source
Fibroblast atlas: Shared and specific cell types across tissues. [PDF]
Liu K+11 more
europepmc +1 more source
33 A Mitotic Inhibitor Produced by Rubella Virus Infection of Human Fibroblasts [PDF]
Stanley A. Plotkin
openalex +1 more source