Results 241 to 250 of about 988,166 (377)

Effects of antitubulins on the redistribution of crosslinked receptors on the surface of fibroblasts and epithelial cells [PDF]

, 1977
L. V. Domnina, O. Pletyushkina, J. M. Vasiliev, Israel M. Gelfand   +3 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

ALKBH5 Inhibits YTHDF2-m6A-Mediated Degradation of RCN1 mRNA to Promote Keloid Formation by Activating IRE1α-XBP1-Mediated ER Stress. [PDF]

J Cosmet Dermatol
Shi M, Zhang L, Bi F, Zhou Z.
europepmc   +1 more source

Influence of Steroids on Fibroblasts. II. The Fibroblast as an Assay System for Topical Anti-Inflammatory Potency of Corticosteroids**Department of Anatomy, University of Utah Medical Center, Salt Lake City, Utah.

, 1967
Ann G. Ruhmann, David L. Berliner
openalex   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, EarlyView.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

YME1L1 Dysfunction Associated With 3-Methylglutaconic Aciduria. [PDF]

J Inherit Metab Dis
Demetriadou A, Grafakou O, Georgiou T, Burska D, Malekkou A, Krizova J, Paramera E, Mavrikiou G, Dionysiou M, Theodosiou A, Sismani C, Anastasiadou V, Ioannou I, Papakonstantinou E, Hansikova H, Drousiotou A, Petrou PP.   +16 more
europepmc   +1 more source

alpha 2 Macroglobulin binding to the plasma membrane of cultured fibroblasts. Diffuse binding followed by clustering in coated regions. [PDF]

, 1979
Mark C. Willingham, Frederick R. Maxfield, Ira Pastan   +2 more
openalex   +1 more source

Rod‐shaped Polymerized Salicylic Acid Particles Modulate Neutrophil Transendothelial Migration in Acute Inflammation

Advanced Healthcare Materials, EarlyView.
Rod‐shaped particles outperform spherical particles of the same volume in preventing neutrophil infiltration to inflamed areas, both in vitro and in vivo. This therapeutic effectiveness is attributed to better cell targeting and decreased cell motility, resulting from the geometry‐driven phagocytosis and inhibited actin polymerization.
M. Valentina Guevara, Emma R. Brannon, Daniel Kupor, Mariana R.N. Lima, Logan D. Piegols, Michael L. Felder, Kathryn E. Uhrich, Omolola Eniola‐Adefeso   +7 more
wiley   +1 more source

Morphological Studies of Effects of Chloroquine Diphosphate on Fibroblasts and Tumor Cells

, 1967
Toshinobu Hiraoka
openalex   +4 more sources

Viscoelastic extracellular matrix enhances epigenetic remodeling and cellular plasticity. [PDF]

Nat Commun
Wu Y, Song Y, Soto J, Hoffman T, Lin X, Zhang A, Chen S, Massad RN, Han X, Qi D, Yeh KW, Fang Z, Eoh J, Gu L, Rowat AC, Gu Z, Li S.   +16 more
europepmc   +1 more source