Results 311 to 320 of about 988,166 (377)

Dynamic substrate topographies drive actin- and vimentin-mediated nuclear mechanoprotection events in human fibroblasts. [PDF]

BMC Biol
Bril M, Boesveld JN, Coelho-Rato LS, Sahlgren CM, Bouten CVC, Kurniawan NA.   +5 more
europepmc   +1 more source

ESCRT III Regulates Lysosomal Perinuclear Clustering by Inhibiting Kinesin 1 Leading to Agnps Cytotoxicity in Human Cells

Advanced Materials Interfaces, EarlyView.
AgNPs cause significant damage upon entering the lysosomes of human fibroblasts, resulting in lysosomal transport disorders and the occurrence of perinuclear clustering (LPC) of lysosomes by promoting apoptosis that is accompanied by a reduction in the expression levels of ESCRT III and Kinesin 1 proteins.
Tiantian Liu, Aiguo Xie, Chao Xing, RuiZhe He, Wei Ni, Yinbo Peng, Peng Xu, Yong Fang   +7 more
wiley   +1 more source

IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts. [PDF]

Open Life Sci
Wang J, Zhang Q, Han Y, Zhang J, Zheng N.   +4 more
europepmc   +1 more source

Nanostructured 316L Stainless Steel Stent Surfaces Improve Corrosion Resistance, and Enhance Endothelization and Hemocompatibility

Advanced Materials Interfaces, EarlyView.
This study investigates the impact of nanostructured surface modification on corrosion resistance, HUVEC functions, and platelet interactions of 316L SS for cardiovascular stents. Nanostructured surfaces enhanced HUVEC proliferation, migration, and angiogenesis‐related gene expression while reducing platelet adhesion and hemolysis.
Yasar Kemal Erdogan, Pelin Mutlu, Batur Ercan   +2 more
wiley   +1 more source

Single-cell RNA sequencing reveals a fibroblast gene signature that promotes T-cell infiltration in muscle-invasive bladder cancer. [PDF]

Commun Biol
Liu Z, Mao X, Xie Y, Yan Y, Wang X, Mi J, Yuan H, Zhang J, Huang C, Chen J, Jili M, Huang S, Zhang Q, Wang F, Mo Z, Yang R.   +15 more
europepmc   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

Lysine Demethylase 1 Has Demethylase-Dependent and Non-Canonical Functions in Myofibroblast Activation in Systemic Sclerosis. [PDF]

Cells
Wasson CW, Perez Barreiro E, Del Galdo F, Riobo-Del Galdo NA.   +3 more
europepmc   +1 more source

Durable Bio‐Based Nanocomposite Coating on Urinary Catheters Prevents Early‐Stage CAUTI‐Associated Pathogenicity

Advanced Materials Interfaces, EarlyView.
A stable bio‐based nanocomposite coating for urinary catheters is developed using a simple, environmentally‐friendly sonochemical process. The coating, integrating antimicrobial, antibiofilm, and antioxidant properties, effectively tackled multiple early‐stage pathogenic factors associated with catheter‐associated urinary tract infections.
Antonio Puertas‐Segura, Kristina Ivanova, Leonardo Martín Pérez, Bzazou El Ouazzani Zine El Abidine, Aleksandra Ivanova, Barış Gökalsın, Gianluca Ciardelli, Tzanko Tzanov   +7 more
wiley   +1 more source

The HOX code of human adult fibroblasts reflects their ectomesenchymal or mesodermal origin. [PDF]

Histochem Cell Biol
Pfeiferová L, Španko M, Šáchová J, Hradilová M, Pienta KJ, Valach J, Machoň V, Výmolová B, Šedo A, Bušek P, Szabo P, Lacina L, Gál P, Kolář M, Smetana K.   +14 more
europepmc   +1 more source

Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation

Advanced Materials Interfaces, EarlyView.
Tuning the morphological properties of granular hydrogels is essential to generate robust lymphatic capillary networks that express key lymphatic gene and protein markers. The study demonstrates that 3D in vitro lymphatic tube formation is controlled not by the mechanical properties of the gel, but by the pore size and topology (periodicity) of the gel
Daniel Montes, Sanjoy Saha, Angela Taglione, Donghyun Paul Jeong, Liao Chen, Fei Fan, Hsueh‐Chia Chang, Donny Hanjaya‐Putra   +7 more
wiley   +1 more source