Results 61 to 70 of about 20,526 (145)

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang, Junxian Zhao, Fangxia Zou, Wanglin Jiang, Jianzhao Zhang, Pengfei Yu, Liang Ye, Xiaolin Sun, Chunmei Li, Jingwei Tian   +9 more
wiley   +1 more source

Serum Vitamin D, Superoxide Dismutase and Catalase Levels in Females with Uterine Fibroid [PDF]

Journal of Sharif Medical & Dental College, 2019
Objective: To determine the serum vitamin D, superoxide dismutase and catalase levels in females with uterine fibroids. Methodology: This study was performed in the Obstetrics & Gynaecology Department of Sharif Medical City Hospital, Lahore after ...
Nazish Jamil , Qurat Ul Ain, Ejaz Ahmad, Sana Javaid, Umer Jamil, Shafeen Zulfiqar   +5 more
doaj  

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, Volume 41, Issue 10, Page 975-997, October 2026.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2025-2034, October 2026.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

Vaginal Hysterectomy Versus Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery Hysterectomy; Results of a Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2035-2043, October 2026.
ABSTRACT Objective To compare Vaginal Hysterectomy (VH) with Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery (NOTES) hysterectomy (VANH) as a day‐care procedure. Design Single‐blind, multicentre randomised controlled trial. Setting Two Dutch non‐academic teaching hospitals.
Ilse P. W. Bekkers, Floor R. M. Wintraecken, Nicol A. C. Smeets, Anne Damoiseaux, Jacques W. M. Maas, Huib A. A. M. van Vliet, Martine M. L. H. Wassen   +6 more
wiley   +1 more source

Functional Outcomes After Vaginal Natural Orifice Transluminal Endoscopic Surgery Hysterectomy: A Systematic Review of Sexual Function and Pelvic Floor Integrity

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 5, October 2026.
ABSTRACT Introduction Vaginal hysterectomy is guideline‐preferred for benign disease, yet uptake is declining. Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) offers enhanced visualisation while optimising recovery; however, impact on functional outcomes remains unclear.
Charlotte M. Wignall, Jane E. McDonnell, Batool Nadim   +2 more
wiley   +1 more source

Transumbilical laparoendoscopic single‐site surgery versus conventional multi‐port laparoscopy for myomectomy: A large single‐center retrospective study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 10, Page 2068-2080, October 2026.
This retrospective observational study compared clinical outcomes from patients who underwent transumbilical laparoendoscopic single‐site surgery (single‐site laparoscopy) or conventional multi‐port laparoscopy for myomectomy. Single‐site laparoscopy and multi‐port laparoscopy showed similar performance in terms of surgical safety.
Xu Yang, Hong Liao, Hongyu Jin, Fan Yang, Sijing Chen, Yu Chen, Jianhong Liu, Xiaorong Qi, Kana Wang, Jinke Li, Qiao Wang, Ying Zheng   +11 more
wiley   +1 more source

Complete excision of pelvic parasitic fibroid using vnotes in morbidly obese patient, case report and review of literature

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
This case report describes the complete excision of a parasitic fibroid using the vaginal natural orifice transluminal endoscopic surgery (vNOTES) technique in a 49-year-old morbidly obese female patient.
Jawaher Alsahabi, Taif alhamad, Reem Alenazi, Ashraf Dawood   +3 more
doaj   +1 more source

Erratum: Gut and genital tract microbiomes: dysbiosis and link to gynecological disorders

Frontiers in Cellular and Infection Microbiology, 2023
Frontiers Production Office
doaj   +1 more source

Hypoxia in Uterine Fibroids: Role in Pathobiology and Therapeutic Opportunities

Oxygen
Uterine fibroids are the most common tumors in females, affecting up to 70% of women worldwide, yet targeted therapeutic options are limited. Oxidative stress has recently surfaced as a key driver of fibroid pathogenesis and provides insights into ...
Sydney L. Olson, Razeen J. Akbar, Adrianna Gorniak, Laura I. Fuhr, Mostafa A. Borahay   +4 more
doaj   +1 more source