Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review
JEADV Clinical Practice, EarlyView.ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos +2 more
wiley +1 more source
Does conservative treatment change the brain in patients with chronic musculoskeletal pain? : a systematic review [PDF]
, 2017 Background: Chronic musculoskeletal pain is characterized by maladaptive central neuroplastic changes. Many observational studies have demonstrated that chronic pain states are associated with brain alterations regarding structure and/or function ...
Cagnie, Barbara +7 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang +4 more
wiley +1 more source
Symptom management and lifestyle interventions for people with fibromyalgia
Advanced Exercise and Health ScienceFibromyalgia is a complex condition with symptoms of hyperalgesia, chronic fatigue, anxiety and depression. Treating fibromyalgia symptoms typically requires pharmacological, psychological and lifestyle interventions to reduce the impact of the disease ...
Cara E. Brown, André R. Nelson
doaj +1 more source
Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. [PDF]
, 2019 BackgroundTo describe the demographic, clinical, and treatment characteristics of youth diagnosed with juvenile primary fibromyalgia syndrome (JPFS) who are seen in pediatric rheumatology clinics.MethodsInformation on demographics, symptoms, functioning,
Boneparth, Alexis D +4 more
core +1 more source
Distinction and mutual Influences between Parkinson's Disease‐related and unrelated Chronic Pain
Movement Disorders Clinical Practice, EarlyView.Abstract Background Chronic pain (i.e. > 3 months) is a common nonmotor symptom in patients with Parkinson's disease (PD), but the attribution to PD is critical for further treatment. Objectives We explored the PD Pain Classification System (PD‐PCS) criteria for the diagnosis of PD‐related pain and mutual influences between PD‐related and PD‐unrelated ...
Jonathan Hunger +11 more
wiley +1 more source
Influence of Moderate Training on Gait and Work Capacity in Fibromyalgia Patients: A Preliminary Field Study [PDF]
, 2002 This field study examined the influence of moderate intensity training on gait patterns and work capacity of individauls with fibromyalgia syndrome (FS).
Dawson, Kimberley A. +2 more
core +2 more sources
A brief review of the pharmacology of amitriptyline and clinical outcomes in treating fibromyalgia [PDF]
, 2017 Fibromyalgia is a complex chronic condition characterized by pain, physical fatigue, sleep disorder and cognitive impairment. Evidence-based guidelines recommend antidepressants as treatments of fibromyalgia where tricyclics are often considered to have ...
Azad +12 more
core +2 more sources
Scientific Evidence Admissibility: Improving Judicial Proceedings to Decrease Erroneous Outcomes [PDF]
, 2019 In the United States, Federal Rules of Evidence 702, the Frye and Daubert standards govern the admissibility of scientific evidence in the courtroom. Some states adopted Frye while others adopted Daubert, causing varying judicial outcomes.
Kwong, Leica
core +1 more source